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Research

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research Smooth muscle cell expression of a constitutive active form of human Profilin1 accelerates cutaneous wound repair

April 2011 in “The FASEB Journal”

This study found that profilin1 protein significantly accelerated wound healing in transgenic mice by reducing wound size and enhancing vascularization and cell migration compared to nontransgenic and 88R/L mice.

research Three isostructural solvates of finasteride and their solid-state characterization

21 citations , October 2009 in “European Journal of Pharmaceutical Sciences”

This study found that drying finasteride solvates at 85 °C for one day produced a metastable anhydrous form.

research Sequence analyses of Type I and Type II chains in human hair and epithelial keratin intermediate filaments: Promiscuous obligate heterodimers, Type II template for molecule formation and a rationale for heterodimer formation

19 citations , December 2006 in “Journal of Structural Biology”

Type I and Type II keratin chains can form heterodimers despite sequence differences.

research INTERACTION OF ZN(II) WITH BOVINE MILK α-CASEIN: STRUCTURE-FUNCTION STUDY

4 citations , August 2011 in “Journal of Food Biochemistry”

This study reports that α-casein in bovine milk can form stable complexes with zinc, potentially useful for fortifying milk-based products to enhance zinc availability.

research Quality evaluation of the Finasteride polymorphic forms I and II in capsules

10 citations , December 2014 in “Journal of Pharmaceutical and Biomedical Analysis”

Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.

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Community Join

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community I stopped finasteride and minoxidil and I regret it

in Progress Pictures 251 upvotes 4 months ago

The user regrets stopping finasteride and minoxidil due to increased hair loss. They have resumed these treatments and are considering a hair transplant.

community Does pyrilutamide degrade to an inactive form if it goes systemic like fluridil

1 upvotes 9 months ago

Pyrilutamide's systemic degradation is unclear, unlike fluridil, which becomes inactive in the body. The discussion focuses on whether pyrilutamide shares this property.

community These yellow scales will be the death of me. Anyways I’m f’ed up

in Treatment 145 upvotes 8 months ago

Managing seborrheic dermatitis using ketoconazole shampoo, Nizoral, and oils like MCT and coconut oil. The user considers shaving their head and consulting a dermatologist.

community Kintor long term safety phase 3

in Research/Science 66 upvotes 1 year ago

Kintor's phase III trial for pyri (KX-826) showed promising safety and efficacy results, with no drug-related sexual dysfunction reported. Users discussed their experiences with pyri, Minoxidil, Dutasteride, and concerns about the validity of the study results.

community KX826 New Phase 3 Trial In China for 2025: 1.0% concentration

62 upvotes 1 year ago

KX-826 is undergoing Phase III trials in China as a potential treatment for male pattern baldness, with some users considering it as an alternative or addition to finasteride and dutasteride. Opinions on its effectiveness vary, with some users reporting positive results and others finding it expensive and ineffective.

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Clinics

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Learn

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learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Alfatradiol

Alfatradiol: What does a form of estrogen have to do with hair loss in men? Alfatradiol (17α-estradiol) is a prescription topical hormone, licensed for androgenetic alopecia in Germany but not FDA-approved. The controlled trial evidence is in women, where it produced stabilisation rather than regrowth and was outperformed by minoxidil; no comparable placebo-controlled trial in men appears to have been published.

learn SCUBE3

Is SCUBE3 available in topical or injectable form, and how is it usually applied in studies? SCUBE3 is not available as a topical or injectable treatment and is not an approved medicine. In the published research it was delivered by microinjecting the recombinant protein into mouse skin and into cultured or grafted human follicles; there are no human clinical trials.

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