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learn Folic acid

How does folic acid support hair follicle health and growth at a cellular level? Folate is required for the DNA synthesis that fast-dividing hair matrix cells depend on, and severe deficiency causes anemia—but no published trial has given folic acid to people with hair loss and measured the result, so a growth effect is a mechanism, not a finding.
Can folic acid help reduce hair loss in men and women, and how should it be taken? Correcting a confirmed folate deficiency is reasonable, but no published trial shows folic acid supplementation reduces hair loss on its own; the evidence is a few small observational studies and reviews that call for proper trials.
Can folic acid be combined with other treatments like minoxidil or biotin for better results? There is no published controlled trial of folic acid combined with minoxidil and biotin, so no synergy has been demonstrated; the vitamins have documented value only for correcting a diagnosed deficiency, and high doses of each carry known cautions.
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Research

5 / 47 results

research A 2018 Approach to Combating Methotrexate Toxicity Folic Acid and Beyond.

September 2018 in “PubMed”

This review discusses various strategies, including vitamin A and dextromethorphan supplementation, to manage methotrexate toxicity and improve adherence in patients with rheumatic diseases, but reports no new clinical results.

research The pharmacology of methotrexate

155 citations , August 1991 in “Journal of The American Academy of Dermatology”

This article reviews methotrexate's pharmacokinetics and toxicity, emphasizing the role of urinary excretion and leucovorin in avoiding most toxic reactions; it provides no new clinical results.

research Effect of FOLFOX6 chemotherapy on serum VEGF expression in advanced colorectal cancer patients

4 citations , February 2019 in “Revista da Associação Médica Brasileira”

This study found that FOLFOX6 chemotherapy significantly decreased serum VEGF and CRP levels in advanced colorectal cancer patients, improved their quality of life as measured by KPS scores, and demonstrated a high overall therapeutic efficacy of 82.72% with manageable side effects.

research Megaloblastic Anemia in a Patient on Peritoneal Dialysis Returning from Kenya

1 citations , October 2020 in “Journal of the American Society of Nephrology”

This case report describes proguanil-related hematologic toxicity in a patient on peritoneal dialysis, suggesting that this malaria prophylaxis should be avoided in chronic kidney disease due to proguanil accumulation.

research Crystalluria with sulphadiazine

5 citations , October 2001 in “British Journal of Ophthalmology”

This abstract describes the initial success of intralesional cidofovir for SCC treatment and states that it has not shown systemic toxicity, but it does not report new clinical trial results.

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community Folic Acid and hair loss

4 upvotes 7 years ago

A user experienced hair loss due to a folic acid deficiency and saw hair regrowth after taking a folic acid supplement. They advise checking for a folic acid deficiency before spending money on other treatments.

community Finasteride and Folic acid correlation?

2 upvotes 1 year ago

Low folic acid may worsen side effects of finasteride. Consult a doctor for personalized advice.

community Lab results from actifolic RU58841

38 upvotes 2 years ago

The post discusses the user's experience with hair loss treatment RU58841, which was tested for quality and found to be 96+% pure. The conversation includes various responses, with some users questioning the safety of the product and others expressing satisfaction with the test results.

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