155 citations
,
  March 2006   in “The American Journal of Medicine”    Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.  
     
           56 citations
,
  July 2008   in “European journal of endocrinology”    Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.  
     
           50 citations
,
  March 2011   in “European Journal of Endocrinology”    Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.  
     
           45 citations
,
  February 2012      Obese women with PCOS are more likely to have fatty liver disease.  
     
           44 citations
,
  May 2008   in “Fertility and Sterility”    Insulin resistance might not be enough to worsen blood vessel function in young, nonobese women with polycystic ovary syndrome.