56 citations
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July 2008 in “European journal of endocrinology” This study found that a 6-month treatment with either metformin or rosiglitazone significantly improved endothelial function in young women with PCOS without any one drug being superior.
45 citations
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February 2012 Among obese women potentially eligible for combined oral contraceptives, this study observed a higher frequency of non-alcoholic fatty liver disease in those with polycystic ovary syndrome.
155 citations
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March 2006 in “The American Journal of Medicine” This study found that young women with polycystic ovary syndrome have altered endothelial function associated with insulin resistance and lower adiponectin levels.
44 citations
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May 2008 in “Fertility and Sterility” In this study, young, nonobese PCOS patients showed significant insulin resistance, but no significant difference in endothelial function compared to healthy controls, suggesting other factors may influence endothelial health.
34 citations
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July 2018 in “American Journal of Physiology-heart and Circulatory Physiology” Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.