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research CAN PATIENTS WITH LUTS AND BPH DISCERN CHANGES IN PEAK URINARY FLOW RATE AND DO SUCH CHANGES CONTRIBUTE TO OVERALL SATISFACTION WITH TREATMENT?

March 2009 in “The Journal of Urology”

This research concludes that finasteride significantly reduces dihydrotestosterone levels and prostate size in men with BPH and may improve urinary symptoms, with greater baseline prostate size predicting more pronounced benefits compared to placebo.

Determination of Finasteride in Human Plasma by Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry with Flow Rate Gradient

research Determination of finasteride in human plasma by liquid chromatography–electrospray ionization tandem mass spectrometry with flow rate gradient

2 citations , October 2010 in “European Journal of Drug Metabolism and Pharmacokinetics”

Researchers developed a quick and sensitive way to measure finasteride in blood using a small sample size.

research Sebum flow dynamics and antidandruff shampoos

2 citations , January 1997 in “Journal of the society of cosmetic chemists”

This study found that among 120 men, two antidandruff shampoos increased sebum excretion rate, while one shampoo decreased sebum output, highlighting distinct effects on the follicular reservoir.

research Development and validation of an UPLC method for determination of content uniformity in low-dose solid drugs products using the design space approach

10 citations , June 2013 in “Talanta”

This study demonstrated a validated UPLC method for analyzing finasteride in low-dose drug products, highlighting methanol content and flow rate as critical factors for method robustness and accuracy.

research Scanning Electrochemical Microscopy of Iontophoretic Transport in Hairless Mouse Skin. Analysis of the Relative Contributions of Diffusion, Migration, and Electroosmosis to Transport in Hair Follicles

50 citations , December 2000 in “Journal of Pharmaceutical Sciences”

This study found that electroosmotic flow through hair follicles significantly contributes to solution flow during iontophoresis in hairless mouse skin.

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Community Join

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community I am starting to believe that bloodflow is the reason for hair loss...

216 upvotes 11 months ago

Hair loss may be linked to blood flow issues, but DHT is considered the main cause. Treatments used include finasteride, RU58841, minoxidil, vitamin D3, microneedling, and dutasteride, but hair loss persists.

community Has anyone tried this method? I have never heard of this before.

1 month ago

The conversation discusses hair loss treatments, focusing on scalp massages to improve blood flow and reduce tension, as suggested in a video by Rob English. However, most users express skepticism, recommending proven treatments like Finasteride, Dutasteride, and Minoxidil instead.

community LLLT vs Minoxidil for Hair Loss Treatment: Which Works Better?

in Research/Science 2 upvotes 1 year ago

Minoxidil and LLLT are compared for treating hair loss, with LLLT showing higher regrowth rates and fewer side effects. LLLT is less time-consuming and more suitable for those with health issues, while Minoxidil requires daily application.

community Thought I would just make this simply post to explain finasteride and minoxidil with an analogy.

in Chat 38 upvotes 1 year ago

Finasteride stops hair loss by blocking DHT, while Minoxidil promotes hair growth by increasing blood flow to hair follicles. Using both can help regrow hair, but results vary by individual.

community Subcutaneous Scalp fat and Hair loss? Interested in others annecdotal experience or knowledge.

6 upvotes 3 years ago

Subcutaneous scalp fat may be linked to hair loss, with theories suggesting that fat loss can lead to reduced blood flow and increased DHT activity, contributing to hair loss. Treatments discussed include PRP/PRF injections and fat transfer to improve scalp thickness and blood flow.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Thymosin Beta 4

learn Vascular Endothelial Growth Factor

Can products that stimulate Vascular Endothelial Growth Factor (VEGF) improve blood flow to hair follicles? Yes, products that stimulate VEGF may improve blood flow to hair follicles.

learn Centella

Ever wonder why your hair doesn’t grow back thick anymore? Maybe your scalp needs better blood flow: centella could help. There is no clinical trial of centella asiatica for hair loss and no study measuring scalp blood flow in people using it; the only hair-related evidence is a 2017 cell-culture study. Centella products are cosmetics that may soothe an irritated scalp, and the link between scalp circulation and pattern hair loss is itself unproven.

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