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GlossaryFilaggrin (FLG)

protein crucial for skin barrier function and hydration

Filaggrin is a protein found in the outermost layers of the skin that plays a crucial role in maintaining the skin's barrier function and hydration. It helps to aggregate keratin fibers, which strengthens the skin and protects against environmental damage. Deficiencies or mutations in the filaggrin gene are linked to skin conditions like eczema and ichthyosis vulgaris.

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2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation

research 2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation

86 citations , August 2011 in “Toxicological sciences”

TCDD speeds up skin barrier formation by increasing certain gene expressions.

research Skin Diseases Associated With Atopic Dermatitis

43 citations , June 2018 in “Clinics in dermatology”

People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.

research Early Arabidopsis Root Hair Growth Stimulation by Pathogenic Strains of Pseudomonas Syringae

24 citations , May 2017 in “Annals of botany”

Pathogenic Pseudomonas syringae bacteria stimulate early root hair growth in Arabidopsis plants.

research Sebaceous Gland, Hair Shaft, and Epidermal Barrier Abnormalities in Keratosis Pilaris with and without Filaggrin Deficiency

23 citations , February 2015 in “The American journal of pathology”

Keratosis pilaris is often linked to genetic mutations and causes skin and hair abnormalities, regardless of those mutations.

research Transcriptomics Analysis Reveals Molecular Alterations Underpinning Spaceflight Dermatology

7 citations , June 2024 in “Communications Medicine”

Spaceflight can harm skin health by altering gene expression, affecting DNA, mitochondria, and skin barriers.

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community Regrowth 21 months, fin, 41 Male

in Progress Pictures 592 upvotes 2 years ago

A user shared their 21-month hair regrowth journey using oral Finasteride 1mg daily and Minoxidil 5% topical applications. Despite initial discouragement due to slow progress, they saw significant improvement, reducing the need for a hair transplant to minor fill-ins at the front hairline.