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research Evolution, mechanism of action, and clinical applications of three generations of antihistamines

3 citations , January 2024 in “Innovaciencia Facultad de Ciencias Exactas Físicas y Naturales”

This review outlines the development and clinical use of three generations of antihistamines, noting that while first-generation drugs have multiple side effects including sedation, second- and third-generation antihistamines offer greater efficacy and safety due to their selective action on peripheral H1 receptors.

research Adverse cutaneous reactions to the new second-generation tyrosine kinase inhibitors (dasatinib, nilotinib) in chronic myeloid leukemia

25 citations , November 2013 in “Journal of the American Academy of Dermatology”

This study observed that 71% of chronic myeloid leukemia patients treated with second-generation tyrosine kinase inhibitors experienced adverse cutaneous reactions, which were generally less severe than those caused by imatinib.

research Safety of dermatologic medications in pregnancy and lactation

73 citations , March 2014 in “Journal of The American Academy of Dermatology”

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

research Androgenetic alopecia risk in allergic rhinitis: A cohort study of immune and antihistamine effects

April 2026 in “World Allergy Organization Journal”

This study found that allergic rhinitis is linked to a higher risk of developing androgenetic alopecia, while second-generation H1-antihistamine use was associated with a reduced risk, especially in younger patients.

research Managing hyperglycemia and rash associated with alpelisib: expert consensus recommendations using the Delphi technique

1 citations , January 2024 in “NPJ breast cancer”

This study, using modified Delphi panels, provided consensus recommendations for managing alpelisib-induced hyperglycemia and rash, advising prophylactic metformin starting for certain risk groups and the use of nonsedating H1 antihistamines and topical steroids for initial rash management.

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community Hate how younger generation makes hair seem more important than it is

in Chat 152 upvotes 7 months ago

A 25-year-old man is worried about his girlfriend noticing his balding and is frustrated by society's focus on looks. He uses minoxidil, finasteride, and dutasteride for hair loss and considers being honest with her.

community Do you think people of previous generations had better hair? What changed?

2171 upvotes 1 year ago

Hair loss is less common now due to accessible treatments like finasteride, minoxidil, and hair transplants. Improved hair care, skincare, and lifestyle changes contribute to people looking younger today.

community Just popped my first fin, excited as hell!

in Finasteride/Dutasteride 154 upvotes 2 years ago

A user shared their excitement about starting finasteride for hair loss after trying various ineffective methods. Other users discussed their experiences with finasteride, including shedding phases and side effects, with one mentioning using topical finasteride and minoxidil.

community Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits

140 upvotes 11 months ago

Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.

community Eirion Therapeutics Announces Potential Breakthrough Treatment for Hair Loss Based on First-in-Man Clinical Trial Results

in Update 415 upvotes 1 year ago

ET-02, a new hair loss treatment, shows promising results with a 6-fold increase in hair count, potentially outperforming minoxidil by activating stem cells in hair follicles. Further trials are ongoing to confirm its efficacy and safety, with potential market release in the future.

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