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research TMT-based quantitative proteomics reveals the genetic mechanisms of secondary hair follicle development in fine-wool sheep

2 citations , February 2025 in “PLoS ONE”

This study used TMT-based quantitative proteomics to analyze the development of secondary hair follicles in fetal sheep, revealing increased follicle density and key proteins involved, such as COL1A1 and THBS4, indicating their potential role in wool quality traits.

research FGF20 Secreted From Dermal Papilla Cells Regulate the Proliferation and Differentiation of Hair Follicle Stem Cells in Fine‐Wool Sheep

3 citations , December 2024 in “Journal of Animal Physiology and Animal Nutrition”

In this study, researchers found that reducing FGF20 expression in dermal papilla cells of fine-wool sheep impedes the growth and differentiation of hair follicle stem cells, providing insights into wool trait improvement and regenerative medicine applications.

research Single-Cell Transcriptome Sequence Profiling on the Morphogenesis of Secondary Hair Follicles in Ordos Fine-Wool Sheep

1 citations , January 2024 in “International journal of molecular sciences”

This study investigated the molecular mechanisms of hair follicle morphogenesis in Ordos fine-wool sheep, identifying differential genes related to primary and secondary hair follicles, and providing important insights for improving wool quality and breeding strategies.

research Effects of TGFBR1 on Proliferation of Dermal Papilla Cells in Fine-Wool Sheep

December 2025 in “Animals”

In this study on fine-wool sheep, researchers found that overexpressing the TGFBR1 gene decreased proliferation of dermal papilla cells by influencing multiple signaling pathways, suggesting TGFBR1 as a negative regulator in hair follicle development.

research A comparison of transcriptomic patterns measured in the skin of Chinese fine and coarse wool sheep breeds

17 citations , October 2017 in “Scientific reports”

This study found that Super Merino sheep have a higher wool follicle density, finer fleece, and distinct gene expression compared to Small Tail Han sheep, which may inform future breeding and genetic interventions.

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community If we can clone a sheep why we can't cure baldness till now

in Research/Science 181 upvotes 1 year ago

Hair loss treatments like Minoxidil, finasteride, and stem cell therapies exist, but a complete cure is hindered by genetic complexity and market dynamics. Cloning hair follicles is considered a potential solution, but it's currently not feasible.

community A little more than a month using red light therapy. I'm surprised by the progress.

263 upvotes 5 months ago

Red light therapy has shown promising results in hair regrowth for the user, who avoids minoxidil and finasteride due to side effects. The user follows a healthy lifestyle with diet, exercise, and sauna use, and will continue monitoring the therapy's effectiveness.

community If grafts are locked in by day 7, why does washing/rubbing the scabs off gently matter?

2 upvotes 7 months ago

The conversation discusses post-hair transplant care, specifically about removing scabs gently after a week, using Vitamin E oil. The user wonders if using harsher methods like steel wool would affect results, but others reassure that if there was no pain or bleeding, it's likely fine.

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