87 citations
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March 2017 in “Journal of Clinical Investigation”
In this study, researchers identified PSENEN mutations that can lead to a form of Dowling-Degos disease, characterized by follicular hyperkeratosis and an increased susceptibility to acne inversa, especially in the presence of certain trigger factors.
11 citations
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September 2012 in “Chinese science bulletin/Chinese Science Bulletin”
This study found that variations in mineral content of hair, such as increased Zr in asthma and respiratory infections, may be linked to different illnesses, suggesting potential diagnostic use.
27 citations
,
January 2017 in “Neuropsychopharmacology”
This study found that acute sleep deprivation enhanced 5α-reductase expression and activity in the rat prefrontal cortex, and finasteride treatment reduced associated psychosis- and mania-like behaviors.
The user has been using finasteride for 5 months to address hair loss and is unsure if progress is being made despite ongoing shedding. Other users believe there is visible improvement and encourage continued use.
Finasteride improved hair but severely reduced libido. Users suggest stopping or adjusting the dosage, considering alternatives like Dutasteride, or consulting a doctor.
A 26-year-old male has been using Minoxidil since 2024 and added Finasteride in March 2026, but after six months, he sees no significant hair regrowth. Users suggest waiting 12-18 months for results, considering Vitamin D3, and possibly trying Dutasteride.
The user started using minoxidil and finasteride for hair loss, with occasional microneedling using a 0.5mm derma-roller. They reported progress and plan to update in six months.
The user experienced significant hair improvement using oral finasteride and minoxidil but is now facing a secondary hair shedding phase after nine months, possibly linked to weight loss or seasonal changes. Despite concerns, others in the conversation suggest that such shedding is normal and temporary.