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research A finasteride patch for the treatment of androgenetic alopecia: A study of promoting permeability strategy using synthetic novel O-acylmenthols combined with ion-pair

October 2024 in “International Journal of Pharmaceutics”

This study aimed to develop a new transdermal patch for treating androgenetic alopecia using finasteride, combined with chemical permeation enhancers to improve drug delivery through the skin, but results of pharmacokinetics and pharmacodynamics evaluations are not reported.

Active Pharmaceutical Ingredient-Ionic Liquids Assisted Follicular Co-Delivery of Ferulic Acid and Finasteride for Enhancing Targeted Anti-Alopecia

research Active pharmaceutical ingredient-ionic liquids assisted follicular co-delivery of ferulic acid and finasteride for enhancing targeted anti-alopecia

November 2023 in “International Journal of Pharmaceutics”

This study reported that a novel ionic liquid delivery system combining ferulic acid and finasteride enhanced the solubility, skin permeation, and effectiveness in promoting hair regrowth in androgenetic alopecia mice, suggesting an improved topical treatment approach.

research Novel iron oxide nanocarriers loading finasteride or dutasteride: Enhanced skin penetration for topical treatment of alopecia

12 citations , July 2020 in “International Journal of Pharmaceutics”

This study found that finasteride- and dutasteride-loaded iron oxide nanoparticles improved drug penetration in the skin, suggesting they may be promising for topical alopecia therapies.

Finasteride Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Ionization Tandem Mass Spectrometry: Application to a Comparative Pharmacokinetics Study

research Finasteride Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Ionization Tandem Mass Spectrometry. Application to a Comparative Pharmacokinetics Study

1 citations , April 2015 in “Drug research”

This study concluded that two different pharmaceutical formulations of finasteride were bioequivalent in terms of rate and extent of absorption based on pharmacokinetic evaluations in a randomized crossover study with 38 volunteers.

research Iontophoretic Transdermal Delivery of Finasteride in Vesicular Invasomal Carriers

15 citations , February 2013 in “Pharmaceutical nanotechnology”

This study found that invasomes enhanced the iontophoretic transdermal delivery of finasteride in rabbits, increasing AUC and T1/2 compared to oral suspension.

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Clinics

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Community Join

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community Dut, Oral fin, Topical Fin+min, Topical min, Multivitamins, Microneedling, Keto, Prp

9 upvotes 1 year ago

The user is using a regimen of 1mg Dutasteride daily, topical finasteride and minoxidil, multivitamins, and supplements to address hair loss but hasn't seen improvement. Suggestions include sticking to one medication, considering oral minoxidil, and possibly a hair transplant, while noting that some treatments may not regrow hair.

community Fin working well but dull orgasm

in Update 21 upvotes 11 months ago

A 31-year-old experienced significant hair regrowth after switching to oral Finasteride but reported dull orgasms as a side effect. Users suggested waiting for the body to adjust, reducing the dosage, or switching to topical Finasteride to manage side effects.

community Well boys... I've joined the Master Race

in Finasteride/Dutasteride 31 upvotes 6 months ago

Finasteride has been effective for maintaining hair density, but due to a slight dip in temple hair, the user switched to dutasteride as an additional measure. Users discuss varying experiences with side effects from finasteride, dutasteride, and minoxidil, highlighting that reactions can differ significantly among individuals.

community Why Fin/Dut Isn't Working for You GPR133: a new hairloss mechanism + Steroid Hair Loss Deep Dive

6 upvotes 2 months ago

Hair loss may be linked to the GPR133 receptor, independent of the androgen receptor pathway. Treatments like finasteride, dutasteride, minoxidil, RU58841, and KX-826 show varying results, with hair loss persisting due to high testosterone and GPR133's role.

community 1 year on Oral Fin/min. Not feeling super great about it.

347 upvotes 3 months ago

The user is unhappy with their hair regrowth after one year on oral finasteride and minoxidil, considering a hair transplant. Many suggest shaving the head or trying more aggressive treatments like RU58841, dutasteride, microneedling, and hair transplants.

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