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research Structure of Intermediate Filament Assembly in Hair Deduced from Hydration Studies Using Small-Angle Neutron Scattering

9 citations , April 2019 in “Journal of structural biology”

Hair's internal fibers are arranged in a pattern that doesn't let much water in, and treatments like oils and heat change how much water hair can absorb.

research A General Mathematical Model for the In Vitro Assembly Dynamics of Intermediate Filament Proteins

5 citations , February 2022 in “Biophysical journal”

The model shows that filament flexibility and amino acid differences affect how fast intermediate filament proteins assemble.

research Mutations in the Helix Termination Motif of Mouse Type I IRS Keratin Genes Impair the Assembly of Keratin Intermediate Filament

27 citations , November 2007 in “Genomics”

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

research Molecular Elements of the Regulatory Control of Keratin Filament Modulator AHF/Trichohyalin in the Hair Follicle

7 citations , July 2008 in “Experimental Dermatology”

The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.

research De Novo Filament Formation by Human Hair Keratins K85 and K35 Follows a Filament Development Pattern Distinct from Cytokeratin Filament Networks

2 citations , April 2021 in “FEBS open bio”

Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.

View more "filament assembly" in research →

Community Join

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community Common hair-loss drug consistently associated with higher rates of psychiatric harm

in Research/Science 183 upvotes 1 week ago

Finasteride and dutasteride can cause psychiatric side effects like depression and suicidal thoughts in some users, especially those with a history of mental health issues. While some users experience positive hair growth results, others face severe psychological effects, raising concerns about their safety and the need for careful monitoring.

community Nov 2023 to today. 1mg finasteride daily since Feb 2024. Considering moving to Dutasteride based on the anecdotes I see on this sub and would like input.

in Progress Pictures 257 upvotes 8 months ago

A 30-year-old is using 1mg finasteride daily and 5% minoxidil inconsistently for hair regrowth, noticing recent progress and considering switching to dutasteride. Users advise continuing the current regimen for at least two years before considering dutasteride, as finasteride and minoxidil are showing positive results.

community New baby hairs are popping out. Question though: what are these black dots on hairline? Clogged pores?

in Finasteride/Dutasteride 39 upvotes 2 months ago

The user is experiencing new hair growth after using oral dutasteride, topical minoxidil, and microneedling, but is concerned about black dots on the hairline, which might be clogged pores or dormant follicles. The user previously used a topical minoxidil/finasteride spray and had good results, despite a shedding phase after switching treatments.

community Not all generic medications are made equal. Some work great, some weaker, and some are dangerous. What Pharmaceutical makes your current/past generic Finasteride?

in Finasteride/Dutasteride 7 upvotes 4 years ago

The conversation discusses the variability in effectiveness and safety of generic finasteride from different manufacturers, with some generics potentially containing impurities. Users shared their experiences with various brands, questioning if different brands affect hair loss treatment outcomes.