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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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research A Novel Small Compound HPH-15 Antagonizes TGF-β/Smad Signaling and Ameliorates Experimental Skin Fibrosis
HPH-15, a new compound, effectively reduces skin fibrosis in experiments without causing harm.
research Melanocortins in Fibroblast Biology: Current Update and Future Perspective for Dermatology
α-MSH may help treat skin inflammation and fibrosis.
research A Human Prenatal Skin Cell Atlas Reveals Immune Cell Regulation of Skin Morphogenesis
Immune cells are essential for early hair and skin development and healing.
research Toward Understanding Scarless Skin Wound Healing and Pathological Scarring
Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.
research Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
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5 / 53 resultscommunity Microneedling at .25 everyday before applying Min
Daily microneedling at 0.25mm before applying minoxidil is debated, with some suggesting weekly microneedling is safer and more effective. Concerns include potential skin damage and systemic absorption, while alternatives like tretinoin are considered safer for enhancing minoxidil absorption.
community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering
Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.
community Peptides that Stop Hair Loss? | In-depth Literature Review Video
Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.
community Microneedling Isn’t Snake Oil — It’s Evidence-Based. Let’s Talk Studies, Not Fear.
Microneedling is supported by research as an effective adjuvant treatment for hair loss, especially when combined with Minoxidil or Finasteride, with minimal side effects if done properly. Concerns about long-term safety and potential risks like infection or fibrosis remain, but many users report positive results.
community Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits
Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.