Search

for
Search:

Research

5 / 1000+ results

research Anagen hair follicles transplanted into mature human scars remodel fibrotic tissue

6 citations , January 2023 in “npj regenerative medicine”

This study found that transplanting hair follicles into human scars may remodel fibrotic tissue and reduce scarring by altering collagen structure and decreasing pro-fibrotic factors.

research Anagen Hair Follicles Transplanted into Mature Human Scars Remodel Fibrotic Tissue

1 citations , January 2021 in “SSRN Electronic Journal”

In this pilot study, the researchers observed that transplanting anagen hair follicles into human scars can promote remodeling of fibrotic tissue and inhibit pro-fibrotic factors, offering potential new treatments for mature scars.

research Exploring the Complexities of TGF-beta Signaling in Keloids: Beyond the Classical Smad Pathway

April 2026 in “International Journal of Molecular Sciences”

This study reviews evidence that in keloid development, transforming growth factor-β (TGF-β) drives fibroblast proliferation and fibrosis not only through the classical Smad-dependent pathway but also via equally important Smad-independent signaling cascades, suggesting these pathways as possible targets for more effective keloid therapies.

research The Multifaceted Functions of TRPV4 and Calcium Oscillations in Tissue Repair

1 citations , January 2024 in “International journal of molecular sciences”

This review article addresses how the TRPV4 ion channel helps cells respond to mechanical and environmental stimuli, discussing its role in calcium signaling crucial for tissue repair and fibrosis across various organ systems, and highlighting potential therapeutic targets from animal and disease models.

research The eosinophilia-myalgia syndrome

4 citations , July 1994 in “Clinics in Dermatology”

This review discusses the emergence and impact of eosinophilia-myalgia syndrome related to L-tryptophan and offers insights into environmental factors affecting sclerodermatous conditions, with no new research findings presented.

View more "fibrotic environment" in research →

Community Join

5 / 54 results

community Day 155 of 5mg oral minoxidil + 0,5mg oral dutasteride daily

in Progress Pictures 103 upvotes 7 months ago

A user shared progress on hair regrowth using 5mg oral minoxidil and 0.5mg oral dutasteride daily, noting small hair growth and no significant side effects except bushier eyebrows. The conversation includes encouragement, personal experiences with hair loss treatments, and discussions on the effectiveness of microneedling.

community The Real Reason For Hair Loss?

8 months ago

Hair loss is linked to scalp fibrosis and tension, which result from chronic mechanical stress and androgenic signaling. Treatments include blocking androgens with finasteride, promoting hair growth with topical minoxidil, and improving scalp mobility through exercises.

community Can't figure out what I'm doing wrong

5 upvotes 8 months ago

A 38-year-old male experienced rapid hair loss progression and tried topical Minoxidil for 15 months without success, then switched to a combination spray with Minoxidil, Finasteride, and Tretinoin for two months, still seeing no improvement. Users suggest patience, as Finasteride can take six months to a year to show results, and recommend considering oral treatments if health permits, while also advising against washing off treatments too soon.

community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells

7 months ago

PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.

community Occipitalis Muscle Tension Theory

13 upvotes 7 months ago

Scalp tension from the occipitalis muscle is theorized to contribute to hair loss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.

View more "fibrotic environment" in community →

Learn

1 / 801 results

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

View more "fibrotic environment" in learn →

Experts

— no results

Try a deeper search in experts →

Clinics

— no results

Try a deeper search in clinics →