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research Expression of Snail1 in the fibrotic dermis of postmenopausal frontal fibrosing alopecia: possible involvement of an epithelial-mesenchymal transition and a review of the Japanese patients

29 citations , February 2010 in “British Journal of Dermatology”

This study explores the expression of Snail1 in the fibrotic dermis of postmenopausal women with frontal fibrosing alopecia, suggesting a possible link to epithelial-mesenchymal transition.

research Issue Information

July 2020 in “Experimental Dermatology”

This discussion of age-related changes in female scalp hair follicles reports no new results, highlighting the structural transformations that may contribute to thinning hair in women as they age.

research Nuevas áreas de conocimiento y la problemática documental: la prospectiva de la paz en la Universidad de Granada

January 1998 in “Boletín de la Asociación Andaluza de Bibliotecarios/Boletín de la Asociación Andaluza de Bibliotecarios”

This study found that ADSC therapy may have significant antiaging effects on photoaged human skin, while PRP increased reticular dermis thickness with a fibrotic appearance.

research Fibroblast heterogeneity: implications for human disease

299 citations , January 2018 in “Journal of Clinical Investigation”

This review explores fibroblast heterogeneity in the mammalian dermis and suggests potential therapeutic applications by targeting fibroblast subtypes, but reports no new experimental results.

research Altered Dermal Fibroblasts in Systemic Sclerosis Display Podoplanin and CD90

47 citations , August 2016 in “American Journal Of Pathology”

This study reports that in systemic sclerosis, CD34+ dermal fibroblasts transition to CD34−, podoplanin+, and CD90+ fibroblasts across the dermis, suggesting a role in unchecked fibrosis.

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community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

59 upvotes 6 months ago

Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

community Is microneedling a risk if you want to have a hair transplant in the future?

in Transplants 13 upvotes 10 months ago

Microneedling may risk scarring, potentially complicating future hair transplants. Alternatives like tretinoin with minoxidil are suggested for better hair growth.

community TCA 35% chemical peel, don't try this shit at home.

11 upvotes 7 months ago

The conversation discusses using a TCA 35% chemical peel on the scalp to potentially improve hair growth by addressing fibrosis and enhancing the effectiveness of topical treatments. The user also mentions trying microneedling and other methods like topical metformin and dutasteride for hair regrowth.

community Almost 6 months on dutasteride and I’m not seeing any improvement

14 upvotes 4 weeks ago

The user switched from finasteride and minoxidil to dutasteride, saw palmetto, and a finasteride lotion but hasn't seen improvement in hair loss after six months. Suggestions include being patient, considering a hair transplant, and adding treatments like microneedling, ketoconazole shampoo, and topical anti-androgens.

community Is this the maximum I can do for my hair without risking my manhood?

17 upvotes 6 months ago

A 23-year-old is using 2.5 mg dutasteride, 5 mg oral minoxidil, RU58841, a laser cap, and PRF injections for hair loss. They are hesitant about microneedling due to concerns about RU58841 absorption and are considering other treatments.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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