3 citations
,
June 2017 in “Reproductive biomedicine online”
In this study, the SRD5A2 rs523349 polymorphism was significantly associated with an increased risk of miscarriage, particularly during the second trimester.
This study demonstrated that high oral doses of finasteride caused external genital abnormalities in male rhesus monkey fetuses, but intravenous doses did not lead to abnormalities.
This rat study suggests that 5α-dihydrotestosterone plays a critical role in inhibiting nipple development in male fetuses by causing the regression of the nipple anlage in utero.
This review discusses the roles of dihydrotestosterone in fetal development and adult diseases, reporting no new clinical results; the authors emphasize the potential of 5α-reductase inhibitors for treatment.
In this review, the authors highlight the occupational risks faced by pregnant urologists, such as radiation and exposure to certain medications, and emphasize the importance of avoiding specific drugs and practicing good hygiene, but note limited data on radiation risk.
Finasteride may pose a risk during pregnancy, so using a condom is recommended if a partner is pregnant. It is advised to stop finasteride before trying to conceive due to potential effects on fetal development.
A 27-year-old male physician improved hair density using minoxidil 5% foam and finasteride 1mg every other day, with initial sexual side effects that subsided. He recommends trying finasteride for a year but warns against dutasteride due to potential liver effects.
The user is seeking a hair loss treatment that doesn't affect beard growth or pose risks to others, using topical finasteride and considering clascoterone and pyrilutamide. They are also using microneedling and ketoconazole shampoo, while avoiding oral finasteride, dutasteride, and minoxidil.
Finasteride is discussed as a hair loss treatment with benefits like reduced prostate enlargement and skin aging, but it is not seen as a "fountain of youth." Users report mixed experiences, including side effects like decreased libido and dry eyes.
CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.