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46,XY Disorders of Sex Development Due to Type 2 5-Alpha Reductase Deficiency in Three Siblings: A Case Report from a Low-Resource Setting

research 46,XY Disorders of Sex Development Due to Type 2 5-Alpha Reductase Deficiency in Three Siblings: A Case Report from a Low-Resource Setting

September 2022 in “Annals of medicine and surgery”

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

research Congenital Adrenal Hyperplasia: Current Insights in Pathophysiology, Diagnostics, and Management

157 citations, May 2021 in “Endocrine Reviews”

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

research Congenital Adrenal Hyperplasia: Comprehensive Overview and Clinical Management

100 citations, May 2011 in “Journal of Pediatric and Adolescent Gynecology”

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

research Congenital Adrenal Hyperplasia: A Comprehensive Review

88 citations, April 2017 in “Journal of Pediatric and Adolescent Gynecology”

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

research Care of the Transgender Patient: The Role of the Gynecologist

86 citations, May 2013 in “American journal of obstetrics and gynecology”

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

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community Not sure what else to do, can’t use anti-androgens (Baseline Hormonal Bloodwork included) need advice badly

in Update 6 upvotes 3 years ago

User experienced feminizing side effects from finasteride and tried RU, alfatradiol, and finasteride without success. They are now considering treatments like Stemoxydine, Zix, Minoxidil, Dermarolling, Eucapil, and a hair transplant.

community 2 months of difference with estradiol and spiro (4 months total w/ estradiol & spiro; 4 years of minoxidil and finasteride) (you should not take estradiol or spiro if you look manly and want to continue looking manly)

in Transgender 115 upvotes 1 month ago

Hair regrowth using estradiol, spironolactone, minoxidil, and finasteride, showing significant improvement over four years. HRT is not advised for cis men solely for hair loss due to feminizing effects.

community Anything stronger than DUT out there?

in Finasteride/Dutasteride 14 upvotes 8 months ago

The conversation discusses seeking a stronger treatment than Dutasteride (DUT) for hair loss. Suggestions include combining DUT with RU58841, increasing DUT dosage, and using transgender hormone replacement therapy or testosterone blockers, though some options may have feminizing side effects.

community why isn’t RU / pyri blamed for feminization, whereas spiro is?

in Treatment 1 year ago

User asks if spironolactone can stack with finasteride and pyrilutamide for hair loss treatment. They question why spironolactone is associated with feminizing effects, while RU/pyri/fluridil, which work similarly, are not.

community Hair loss steps, guide to beginners or anyone experiencing hair loss

in Treatment 1 upvotes 1 month ago

The conversation discusses a hair loss treatment regimen involving finasteride, dutasteride, spironolactone, bicalutamide, oral estradiol, microneedling, and minoxidil. The regimen aims to reduce androgenic alopecia by blocking DHT and androgens, with a caution about potential feminizing effects.

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