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research The Mesenchymal Component of Hair Follicle Neogenesis: Background, Methods, and Molecular Characterization

131 citations, July 2009 in “Experimental Dermatology”

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

research Fibroblast Heterogeneity: Implications for Human Disease

299 citations, January 2018 in “Journal of Clinical Investigation”

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

research Tissue Engineering and Regeneration of the Human Hair Follicle in Androgenetic Alopecia: Literature Review

4 citations, January 2022 in “Life”

Tissue engineering could be a future solution for hair loss, but it's currently expensive, complex, and hard to apply in real-world treatments.

research TGF-β2 Is Specifically Expressed in Human Dermal Papilla Cells and Modulates Hair Folliculogenesis

43 citations, March 2009 in “Journal of Cellular and Molecular Medicine”

TGF-β2 plays a key role in human hair growth and development.

Topical Mechlorethamine Restores Autoimmune-Arrested Follicular Activity in Mice with an Alopecia Areata-Like Disease by Targeting Infiltrated Lymphocytes

research Topical Mechlorethamine Restores Autoimmune-Arrested Follicular Activity in Mice with an Alopecia Areata-Like Disease by Targeting Infiltrated Lymphocytes

19 citations, March 2003 in “Journal of Investigative Dermatology”

Mechlorethamine treatment regrew hair in mice by killing immune cells causing hair loss without harming hair follicles.

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community Why is everyone not directly advised Dutasteride?

in Finasteride/Dutasteride 169 upvotes 5 months ago

Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.