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GlossaryForeign Body Reaction (FBR)

body's immune response to an implanted or invasive object

A Foreign Body Reaction (FBR) is the body's immune response to a foreign object that has entered the tissue, such as a splinter, surgical implant, or even hair transplants. This reaction involves inflammation, the formation of a fibrous capsule around the object, and the recruitment of immune cells to the site in an attempt to isolate or expel the foreign material.

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research Tracing Immune Cells Around Biomaterials With Spatial Anchors During Large-Scale Wound Regeneration

1 citations , March 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

Biodegradable scaffolds help regenerate wounds and hair by activating the immune system.

research Biocompatibility Of Kaps-Depleted Residual Hair

May 2024 in “bioRxiv (Cold Spring Harbor Laboratory)”

KAP-depleted hair causes less immune response and is more biocompatible for implants.

research Exploring the Overlooked Roles and Mechanisms of Fibroblasts in the Foreign Body Response

17 citations , July 2022 in “Advances in Wound Care”

Fibroblasts play a crucial role in the body's response to implants, needing more research for better treatments.

research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors

20 citations , March 2005 in “Current Medicinal Chemistry”

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

research Relative Binding Affinity of Novel Steroids to Androgen Receptors in Hamster Prostate

5 citations , January 2005 in “Journal of Enzyme Inhibition and Medicinal Chemistry”

New steroids were effective in blocking male hormone receptors in hamster prostates.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 41 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.