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GlossaryForeign Body Reaction (FBR)

body's immune response to an implanted or invasive object

A Foreign Body Reaction (FBR) is the body's immune response to a foreign object that has entered the tissue, such as a splinter, surgical implant, or even hair transplants. This reaction involves inflammation, the formation of a fibrous capsule around the object, and the recruitment of immune cells to the site in an attempt to isolate or expel the foreign material.

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research Biocompatibility Of Kaps-Depleted Residual Hair

May 2024 in “bioRxiv (Cold Spring Harbor Laboratory)”

KAP-depleted hair causes less immune response and is more biocompatible for implants.

research Frontal Fibrosing Alopecia Versus Lichen Planopilaris: A Clinicopathological Study

126 citations, April 2006 in “International Journal of Dermatology”

The conclusion is that FFA and LPP have similar scalp biopsy features, making them hard to distinguish histologically, and FFA may be a specific kind of scarring hair loss.

research The Role of AUTS2 in Neurodevelopment and Human Evolution

118 citations, October 2013 in “Trends in Genetics”

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

research Mechanical Forces in Skin Disorders

65 citations, March 2018 in “Journal of Dermatological Science”

Skin problems can be caused or worsened by physical forces and pressure on the skin.

research Dermal Macrophage and Its Potential in Inducing Hair Follicle Regeneration

2 citations, March 2021 in “Molecular Immunology”

Dermal macrophages might help regrow hair.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.