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research Regeneration of fat cells from myofibroblasts during wound healing

408 citations , January 2017 in “Science”

This study found that hair follicles in mice and humans can convert wound-related myofibroblasts into adipocytes, suggesting a potential pathway to reduce scar formation by activating BMP signaling.

research AB1159 HIGH FAT DIET AND THE ADIPOCYTE TO MYOFIBROBLAST TRANSITION: IMPLICATIONS FOR SYSTEMIC SCLEROSIS CUTANEOUS FIBROSIS

June 2024

This pilot study found that a high fat lard diet may protect against fibrosis and affect the hair follicle cycle in a mouse model of systemic sclerosis, unlike a high fat coconut oil diet.

research Skinny Fat Cells Stimulate Wound Healing

9 citations , June 2020 in “Cell stem cell”

This study found that dermal adipocytes contribute to efficient skin repair by releasing fatty acids that recruit macrophages and transforming into myofibroblasts that aid wound healing.

research Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair

124 citations , June 2020 in “Cell Stem Cell”

This study found that in mice, dermal adipocytes initiate inflammation and aid repair after skin injury by releasing lipids, suggesting a role in managing inflammatory diseases and impaired wound healing.

research Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds

301 citations , February 2019 in “Nature Communications”

In this study, researchers found that wound healing in mouse skin recruits diverse fibroblasts, including myeloid-derived cells, which contribute to regenerating adipocytes.

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community The Real Reason For Hair Loss?

8 months ago

Hair loss is linked to scalp fibrosis and tension, which result from chronic mechanical stress and androgenic signaling. Treatments include blocking androgens with finasteride, promoting hair growth with topical minoxidil, and improving scalp mobility through exercises.