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research Molecular Evolution and Protein Structure Variation of Dkk Family

3 citations , September 2023 in “Genes”

This study analyzed the molecular evolution and functional divergence of the Dkk gene family, finding accelerated evolution in Aves and Reptilia and identifying functional differences that may impact hair follicle development via Wnt signaling inhibition.

research Structure and hair follicle-specific expression of genes encoding the rat high sulfur protein B2 family

12 citations , February 1998 in “Gene”

This study identified two high sulfur protein genes, B2E and B2F, in rats, which are expressed in hair cortical cells during anagen and contribute to hair fiber production.

Characteristics of the Microscopic Hair Structure of Domestic Mammals from the Equidae Family

research Characteristics of the microscopic hair structure of domestic mammals from Equidae family

December 2019 in “Ukrainian Journal of Veterinary and Agricultural Sciences”

This study found that examining the microscopic and ultramicroscopic structures of donkey and horse hair can help differentiate between the species based on distinct differences in hair cuticle and brain substance patterns.

Structural and Functional Studies of L-PGDS and SMPDL3A Enzymes in Lipid Signaling Family

research Structural & functional studies of L-PGDS and SMPDL3A enzymes in lipid signaling family

October 2019

This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.

research Hair follicle differentiation: expression, structure and evolutionary conservation of the hair type II keratin intermediate filament gene family

65 citations , February 1992 in “Development”

This study characterizes a type II keratin intermediate filament gene family involved in early sheep follicle differentiation, detailing gene expression patterns and sequences in hair cortical cells.

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community Balding while your father has a full head of hair must suck

in Finasteride/Dutasteride 261 upvotes 1 year ago

Unexpected hair loss despite family members having full hair. Treatments include finasteride, minoxidil, and dutasteride.

community Do hair follicles dies or are dormant ?

in Finasteride/Dutasteride 92 upvotes 1 year ago

Hair follicles can be dormant and potentially revived with treatments like finasteride and minoxidil, but irreversible loss occurs if certain structures are destroyed. Early intervention is more effective, and additional methods like microneedling may help.

community DUPA, Non Responders and Connective Tissue Disorders

8 upvotes 1 year ago

A 27-year-old male with diffuse hair loss, including the donor area, did not respond to finasteride, dutasteride, or minoxidil. He suspects his hair loss may be linked to a mild connective tissue disorder, possibly affecting the structural support of hair follicles, rather than being purely hormonal.

community Does Min Act Differently If MPB Is Not Genetic

5 upvotes 4 months ago

The conversation discusses hair loss caused by Trenbolone use, with suggestions to stop using it and consider treatments like Minoxidil, Dutasteride, and RU58841. It highlights that Minoxidil may temporarily regrow hair, but stopping Trenbolone is crucial to prevent further hair loss.

community One year on dutasteride and minoxidil. In depth review below

in Progress Pictures 44 upvotes 1 month ago

A 22-year-old has been using oral dutasteride and minoxidil for a year to prevent hair loss, experiencing some thinning at the temples but maintaining a full head of hair. The user increased the dosage after consulting a dermatologist and is considering adding ketoconazole shampoo for additional scalp DHT suppression.

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learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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