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autoimmune disorder causing patchy hair loss
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5 / 801 results- What makes alopecia areata different from other types of hair loss, and can topical Salicylic acid treatments help regrow the affected areas? Alopecia areata is an autoimmune condition, and salicylic acid does not promote hair regrowth.
- What is tofacitinib, and why is it discussed in relation to autoimmune-related hair loss such as alopecia areata? Tofacitinib is a prescription JAK inhibitor approved for rheumatoid arthritis, psoriatic arthritis and ulcerative colitis — not for alopecia areata. It is discussed for hair loss because a 2014 case report and a 2016 open-label trial reported regrowth in severe alopecia areata, but that use is off-label, the regrowth relapsed after stopping, and the drug carries an FDA boxed warning.
- Heard alopecia areata leaves scar-like spots? Some peptides are helping those areas regrow hair. Alopecia areata patches usually still have living follicles. Peptides are being studied as a possible add-on, but the evidence is small and early. See a dermatologist for treatment.
- What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 may target non-scarring alopecia, particularly androgenetic alopecia.
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a JAK inhibitor for alopecia areata and other autoimmune conditions
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Research
5 / 1000+ results
research A clinical case of familial alopecia areata in combination with immune pathology
In this case report, researchers observed that two sisters with congenital immune disorders experienced partial hair regrowth while receiving tofacitinib for severe alopecia areata, highlighting the need for careful clinical and laboratory monitoring due to potential infection risks associated with JAK inhibitor therapy.
research Familial aggregation of alopecia areata
This review examines the immunological aspects of alopecia areata, focusing on genetic, neuroimmunological, and immune privilege factors, but does not report new clinical findings.
research Familial patterns of alopecia areata: A systematic review and meta-analysis
This systematic review and meta-analysis reports a significant familial risk of autoimmune and related conditions among relatives of individuals with Alopecia Areata, highlighting the importance of comprehensive family monitoring and genetic counseling.
research Familial coexistence of vitiligo and alopecia areata: successful treatment with intralesional corticosteroids
This case study reports co-localized vitiligo and alopecia areata on the scalp of a 33-year-old Indian male, with marked improvement following intralesional corticosteroid treatment, suggesting a shared autoimmune pathogenesis.
research Major Histocompatibility Complex Class I Chain-Related Gene A Polymorphisms and Extended Haplotypes Are Associated with Familial Alopecia Areata
This study found significant associations between certain MICA variants and haplotypes with alopecia areata, suggesting MICA as a potential candidate gene linked to the disease's susceptibility and severity.
Community Join
5 / 1000+ resultscommunity The Real Cause Of Androgenetic Alopecia
Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.
community DHT Isn’t the Only Factor in Hair Loss and That Might Be the Key to a Real Cure
Hair loss involves more than just DHT, with genetic factors like TRPS affecting hair follicles. Treatments such as Amplifica's AMP-601 and AMP-303 target stem cells for potential hair growth solutions.
community Age 18 vs Age 25, the importance of starting early
An 18-year-old began using Finasteride and Topical Minoxidil for hair loss, later switching to Oral Minoxidil and Dutasteride by age 25. The conversation emphasizes early treatment, potential side effects, and differing opinions on medication effectiveness.
community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders
Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.
community The mechanism of androgenic alopecia
DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.
Clinics
6 / 13 results- 31Hair Loss TreatmentsAlopecia Areata TreatmentLondon, England · GB
- 14TrichologyAlopecia Areata Germany e.V.Krefeld, Nordrhein-Westfalen · DE
- 18Hair Loss TreatmentsAlopecia Areata SummitChicago, IL · US
- 8Hair SystemsArt of AlopeciaHouston, TX · US
- 26
Hair Loss TreatmentsHairWise - Hair Loss Clinic & Alopecia Areata SpecialistMiami, FL · US - 15Hair SystemsGot Alopecia? Call Keisha!Atlanta, GA · US
Experts
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