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research Adipose Mesenchymal Stem Cell‐Derived Exosomes Versus Platelet‐Rich Plasma Treatment for Photoaged Facial Skin: An Investigator‐Blinded, Split‐Face, Non‐Inferiority Trial

13 citations , May 2025 in “Journal of Cosmetic Dermatology”

This study reports that adipose mesenchymal stem cell-derived exosomes and platelet-rich plasma both improved the condition of photoaged facial skin, with no significant difference in effectiveness between the two treatments, potentially offering a quicker and less invasive option for patients.

research A Comparative Study on Adipose-Derived Mesenchymal Stem Cells Secretome Delivery Using Microneedling and Fractional CO2 Laser for Facial Skin Rejuvenation [Response to Letter]

March 2023 in “Clinical Cosmetic and Investigational Dermatology”

This commentary reviews methods for delivering adipose-derived mesenchymal stem cell secretome for facial skin rejuvenation and does not report new clinical results; the authors discuss addressing concerns about administration methods and product characterization.

Exosomes Derived from Adipose Tissue-Derived Mesenchymal Stem Cells for the Treatment of Dupilumab-Related Facial Redness in Patients with Atopic Dermatitis

research 20 Exosomes derived from adipose tissue-derived mesenchymal stem cells (ASCE) for the treatment of dupilumab-related facial redness in patients with atopic dermatitis

November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

In this study, topical application of adipose stem cell exosomes was found to reduce facial redness in atopic dermatitis patients treated with dupilumab, while improving skin hydration and decreasing inflammation markers over 12 weeks.

research Secretome of Mesenchymal Stromal Cells as a Possible Innovative Therapeutic Tool in Facial Nerve Injury Treatment

2 citations , January 2023 in “BioMed Research International”

This review discusses the potential of mesenchymal stromal cell secretome therapies for facial nerve palsy, emphasizing their standardization advantages over cell transplantation, but provides no new clinical results.

research Retinoic Acid and Mouse Skin Morphogenesis. II. Role of Epidermal Competence in Hair Glandular Metaplasia

16 citations , November 1994 in “Developmental Biology”

Retinoic acid causes gland formation instead of hair in mouse skin by altering epidermal and dermal interactions.

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Community Join

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community DHT Isn’t the Only Factor in Hair Loss and That Might Be the Key to a Real Cure

373 upvotes 6 months ago

Hair loss involves more than just DHT, with genetic factors like TRPS affecting hair follicles. Treatments such as Amplifica's AMP-601 and AMP-303 target stem cells for potential hair growth solutions.

community Comprehensive Microneedling Guide

292 upvotes 4 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community The Real Cause Of Androgenetic Alopecia

675 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Facial bloating/aging on oral Min

4 upvotes 6 days ago

Oral minoxidil can cause facial bloating, leading to a puffy appearance. Some users report improvement after stopping the medication.

community Say goodbye to facial hair development Dutasteride

39 upvotes 1 month ago

A 19-year-old started Dutasteride at 17 to combat aggressive hair thinning, which halted his facial hair development despite having strong beard genetics. He also used oral and topical Minoxidil without success for facial hair, and the discussion highlights the impact of DHT blockers on beard growth.

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Learn

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learn Hair Transplant

Will the transplanted beard hair from a hair transplant grow like natural facial hair? Transplanted beard hair grows like natural facial hair over time.

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