November 2023 in “Research Square (Research Square)”
In this study, researchers used NIR-II fluorescence imaging to track the survival and migration of EPI-NCSCs in rat models, finding that these stem cells aided in repairing facial nerve defects when applied via acellular nerve allografts.
The researchers reported that using exosomes from hairfollicle stem cells with acellular nerve allografts helped bridge facial nerve defects in rats and may match the effectiveness of autograft therapy.
196 citations
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March 2016 in “Nature Communications”
In this study, researchers identified 18 genetic associations with scalp and facialhair traits in Latin Americans, including novel loci for hair greying and balding, with implications for understanding hair evolution.
26 citations
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January 2013 in “BioMed Research International”
This review discusses the hormonal influences on hair cycling disorders in post-partum and postmenopausal women and notes the lack of evidence for effective targeted treatments.
Oral minoxidil can cause multiple facial hairs to grow from one follicle, known as Pili Multigemini, leading to ingrown hairs and zits. Users report increased facial and body hair growth, with some experiencing fewer issues after switching to dutasteride.
Hairfollicles are mostly dormant but can be reactivated with treatments like minoxidil, finasteride, and microneedling. A new drug, PP405, shows promise for hair regrowth but may not be available until 2027-2028.
Beard gains from minoxidil are usually permanent due to facialhairfollicles' lower sensitivity to DHT. Scalp hair requires ongoing DHT suppression with treatments like finasteride, dutasteride, and RU58841 to maintain gains after stopping minoxidil.
The user experienced significant hairline improvement using 10mg oral minoxidil and 0.5mg dutasteride daily but also saw increased body and facialhair growth. They are considering reducing the minoxidil dose due to side effects and exploring laser hair removal options.
Minoxidil may suppress androgen activity in hairfollicles, potentially aiding in hair growth and prostate cancer treatment. Users discuss the effectiveness of minoxidil and finasteride for hair maintenance and regrowth, with some preferring topical applications over oral due to safety concerns.