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research Alopecia: unapproved treatments or indications

22 citations , March 2000 in “Clinics in Dermatology”

This study developed a method using HPLC with UV-DAD and ESI-MS detection to identify prohibited substances like minoxidil and hormones in cosmetic products advertised online for hair loss and skin conditions.

research Novel agents for the treatment of alopecia

29 citations , December 1998 in “Seminars in Cutaneous Medicine and Surgery”

This review examines recent approvals and emerging treatments for androgenetic alopecia, discussing newly approved drugs like Propecia and Rogaine Extra Strength 5%, but without presenting new clinical results.

A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

research A randomized clinical trial of 5% topical minoxidil versus 2% topical minoxidil and placebo in the treatment of androgenetic alopecia in men

269 citations , August 2002 in “Journal of The American Academy of Dermatology”

This study found that 5% topical minoxidil significantly increased hair regrowth and improved psychosocial perceptions of hair loss in men with androgenetic alopecia compared to 2% topical minoxidil and placebo over 48 weeks.

research Book Review Pediatric Endocrinology: A Practical Clinical Guide (Contemporary Endocrinology.) Edited by Sally Radovick and Margaret H. MacGillivray. 582 pp., illustrated. Totowa, N.J., Humana, 2003. $165. 0-89603-946-3

February 2004 in “The New England Journal of Medicine”

The book is a comprehensive and current guide on hair disorders, with minor flaws.

research Book Review Disorders of Hair Growth: Diagnosis and Treatment Second edition. Edited by Elise A. Olsen. 544 pp., illustrated. New York, McGraw-Hill, 2003. $195. 0-07-136494-3

February 2004 in “The New England Journal of Medicine”

The book is a comprehensive resource on hair disorders, but lacks information on some conditions.

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learn Overview

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

Minoxidil 2%, 5% and 10% which is better to use? In a randomized trial in men, 5% topical minoxidil produced more hair growth than 2%. There is no approved 10% product and no head-to-head trial showing it beats 5%; higher strengths mainly add irritation and systemic absorption. Approved strengths differ by sex, so check the label for your product.

learn Finasteride

Is Finasteride unbeatable or are there equally powerful alternatives? Trials report finasteride as the single medication with the strongest measured effect in male androgenetic alopecia, while dutasteride, minoxidil, topical finasteride, PRP, LLLT and microneedling all have supporting studies and are often reported to work better in combination. Finasteride, dutasteride and oral minoxidil are prescription-only, and several of these uses are off-label.