9 citations
,
January 2017 in “Organic Process Research & Development” This article describes the efficient synthesis of (S)-N-(2-bromo-6-methoxypyridin-4-yl)-2-hydroxy-2,4-dimethylpentanamide, a novel topical antiandrogen, with high purity and enantiomeric excess but reports no pharmacological results.
July 2021 in “Journal of dermatology research and therapy” This article discusses the mechanisms by which Cutibacterium acnes contributes to acne vulgaris and mentions potential triggers like UV light and tobacco, but it reports no new clinical results.
17 citations
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January 2004 in “European journal of obstetrics, gynecology, and reproductive biology/European journal of obstetrics & gynecology and reproductive biology” This review discusses the use of ethinylestradiol combined with antiandrogenic progestin for treating androgenisation symptoms and improving metabolic and menstrual health in women, but it does not provide new clinical data.
4 citations
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January 1991 in “Journal of dermatological treatment” This study found that GnRH-A treatment significantly reduced hirsuties scores in women with mild idiopathic hirsuties but did not affect hair growth rate or diameter.
In this study, hyperandrogenemia was observed in 78.2% of Greek women with polycystic ovary syndrome, with testosterone being the most commonly elevated androgen and acne the most frequent clinical feature.