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research Evidence based medicine: a movement in crisis?

1647 citations , June 2014 in “BMJ”

This article argues that while evidence-based medicine has provided many benefits, it has also led to negative unintended consequences, and proposes a renewed focus on integrating context and professional expertise to improve patient treatment.

research Evidence-Based and Potential Benefits of Metformin in the Polycystic Ovary Syndrome: A Comprehensive Review

343 citations , December 2008 in “Endocrine Reviews”

This review discusses the various evidence-based and potential applications of metformin in treating and preventing symptoms and complications associated with polycystic ovary syndrome but reports no new clinical results.

research Evidence-based (S3) guideline for the treatment of androgenetic alopecia in women and in men

198 citations , October 2011 in “Journal der Deutschen Dermatologischen Gesellschaft”

This article discusses the development of an evidence-based guideline for treating androgenetic alopecia and reports no new research results.

research Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment

182 citations , May 2003 in “Development”

This study found that Myc activation in mouse epidermis impairs keratinocyte adhesion and motility by downregulating extracellular matrix and cytoskeleton proteins, affecting hair lineage differentiation.

research Evidence-based (S3) guideline for the treatment of androgenetic alopecia in women and in men – short version

145 citations , November 2017 in “Journal of The European Academy of Dermatology and Venereology”

This guideline review by the European Dermatology Forum evaluates current treatments for androgenetic alopecia but reports no new research findings, aiming to assist dermatologists in selecting safe and effective therapies.

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Community Join

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community Evidence of DUT shedding in clinical trials?

in Finasteride/Dutasteride 6 upvotes 1 month ago

Switching from finasteride to dutasteride may cause increased hair shedding, which is not well-documented in clinical trials. Some users report success with dutasteride, but experiences vary, and expectations may influence perceptions of effectiveness.

community Evidence-based natural treatment that works for me

3 years ago

A user shared a natural hair loss treatment involving micro-needling and a mix of turmeric, cinnamon, and coconut oil, claiming it effectively thickened their hair. The treatment is applied every two to three weeks, but some users expressed skepticism and requested photographic evidence.

community scientific evidence of the effect of minoxidil on collagen synthesis

in Minoxidil 3 upvotes 11 months ago

Minoxidil may inhibit collagen synthesis at high concentrations, with anecdotal reports of skin aging but limited research. Dermatologists and other specialists show little interest in studying minoxidil's side effects.

community Scientific evidence for Minoxidil causing skin ageing?

5 upvotes 3 years ago

Minoxidil may reduce collagen, potentially affecting skin, but evidence is limited. Users suggest precautions like moisturizing and using retinoids to mitigate possible side effects.

community Looking for evidence-based additions to a 1% topical finasteride formulation

1 upvotes 3 months ago

The conversation discusses enhancing a 1% topical finasteride solution for hair retention and regrowth with additional ingredients like melatonin, caffeine, and adenosine, while considering stability and efficacy. Concerns are raised about the stability of topical finasteride, with suggestions to use oral finasteride or obtain fresh formulations from a trusted pharmacy.

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Learn

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learn Omega 3

Do omega-3 supplements help with hair loss? What the evidence says Evidence that omega-3 supplements help hair is weak: small, combination-product trials, one run by the maker. Omega-3 capsules have side effects and interactions; ask a doctor first.

learn capsicum

Is there real evidence behind “spicy” treatments for thinning hair? Limited scientific evidence supports the effectiveness of spicy treatments for hair thinning.

learn Stem Cell Factor

Is there evidence that stem cell factor treatments visibly improve hair, and how long would it take? There is no clinical evidence that stem cell factor treatments improve hair; if any effect exists, it could not be judged before 3 to 6 months.

learn Vitis vinifera

Is there evidence for using Vitis vinifera for hair loss? Grape extract has not been tested for hair loss in people; the one small human trial used an apple compound.

learn Centella

Hormone-related scalp sensitivity: is there evidence for a centella mask? Centella asiatica has anti-inflammatory and wound-healing effects in animal and cell studies, but no published research has tested a centella scalp mask on the human scalp, in hormonal contexts or otherwise, and no community reports were found of one being used this way.

learn Saw Palmetto

A plant extract with weak evidence for hair loss. In the one comparison study it did much less than finasteride, and it has its own side effects.

learn Redensyl

Cosmetic ingredient blend marketed for thinning hair; the evidence is supplier studies and small multi-ingredient product trials.

learn Lavender

Plant oil used in scalp products; hair-growth evidence is from one mouse study. It can cause skin allergy, and case reports link lavender products to breast growth in children.

learn Estradiol

A prescription estrogen hormone that is not approved for hair loss. Evidence that it regrows hair is weak, and it carries serious whole-body risks, including a US boxed warning.

learn Dexpanthenol

Provitamin B5 used in hair and skin products as a moisturiser; evidence for hair growth is limited to lab studies and small uncontrolled reports.

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Clinics

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Trichology
Umbrella Clinic - Evidence-Based Trichology & Cosmetology in KyivKyiv · UA

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