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research Topical Spironolactone in the Treatment of Evaporative Dry Eye Disease

1 citations , June 2023 in “Cureus”

In a retrospective study, researchers found that topical spironolactone improved tear film quality and reduced inflammation related to meibomian gland dysfunction and evaporative dry eye in patients, demonstrating good tolerability and suggesting it as a potential therapy for managing the condition.

research Keratinisation status and cytokeratins of the human Meibomian gland epithelium

5 citations , September 2009 in “Acta Ophthalmologica”

This study found that the Meibomian gland shares structural and cytokeratin composition similarities with hair follicles, and plays a role in hyper-keratinisation observed in obstructive Meibomian gland dysfunction.

research Evaluation of dry eye and Meibomian gland dysfunction in female androgenetic alopecia patients

July 2021 in “International Ophthalmology”

Female hair loss patients more likely to have dry eye and gland issues.

The Association Between 5α-Reductase Inhibitors and the Presence of Subsequent Dry Eye Disease in Androgenetic Alopecia: A TriNetX Database Study

research The Association Between 5α-Reductase Inhibitors and the Presence of Subsequent Dry Eye Disease in Androgenetic Alopecia: A TriNetX Database Study

December 2025 in “Cureus”

In this retrospective cohort study, researchers found that patients with androgenetic alopecia using 5α-reductase inhibitors had a significantly higher risk of developing dry eye disease compared to those not using these medications.

research Identification of a blink frequency threshold for maintaining tear film stability in young adults with dry eye symptoms

November 2025 in “Scientific Reports”

This study found that a blink frequency of at least 20 blinks per minute is necessary to maintain tear film stability in young participants with dry eye symptoms, with lower frequencies significantly worsening various indicators of eye dryness.

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community Why leave minoxidil on the scalp for more than 30 minutes?

49 upvotes 2 years ago

Minoxidil should be left on the scalp for at least 4-6 hours for effective absorption, even if it feels dry after 30 minutes. The skin's interaction with the chemical continues regardless of the solution's evaporation.

community The day they make a pill that only targets DHT production in the scalp

in Finasteride/Dutasteride 29 upvotes 1 year ago

Reducing DHT in the scalp is ideal for hair retention, with topical finasteride and dutasteride being common treatments. Some users report side effects like reduced libido, while others experiment with higher doses for regrowth.

community My personal experience/observations fighting AGA seriously for 5 years

50 upvotes 1 year ago

Minoxidil with alcohol and propylene glycol was more effective than non-alcohol versions, and RU58841 worked best in a non-water-based solution. Oral finasteride showed better results than topical, despite side effects; microneedling and tretinoin worsened hair loss, and PRP was only helpful when younger.

community Progress 9 months finesterid 2,5 months minoxidil

1247 upvotes 1 year ago

The user experienced significant hair regrowth using finasteride for 9 months and minoxidil foam for 2.5 months, with minimal side effects. Hair thickening was noticed after 4-5 months, with no significant shedding.

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