18 citations
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April 2016 in “Endocrinology and Metabolism Clinics of North America” This review discusses the diagnostic challenges of PCOS in adolescents, noting that the persistence of hyperandrogenism and oligomenorrhea is required for diagnosis, while genetic studies suggest involvement of the hypothalamic-pituitary-ovarian axis.
1 citations
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January 2014 in “Side effects of drugs annual” Hormonal contraceptives and related compounds can increase health risks like thrombosis and affect sexual function.
1 citations
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November 2011 in “Open access journal of contraception” This article reviews the role of androgens and oral contraceptives in acne pathogenesis and management but presents no new clinical results.
451 citations
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March 2005 in “Endocrine Reviews” This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.
37 citations
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October 2006 in “Steroids” This paper describes recent advancements in the synthesis of thiasteroids but reports no new experimental results, noting that introducing heteroatoms in steroidal structures has potential biological effects.