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Research

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research Leuprolide and estrogen versus oral contraceptive pills for the treatment of hirsutism: a prospective randomized study.

74 citations , December 1995 in “The Journal of Clinical Endocrinology & Metabolism”

This study found that treatment with leuprolide plus cyclic estrogen/progestin may lead to a faster and greater improvement in hirsutism compared to a standard oral contraceptive regimen.

research The Use/Abuse of Oral Contraceptive Pills Among Males: A Mixed-Method Explanatory Sequential Study Over Jordanian Community Pharmacists

1 citations , March 2021 in “medRxiv (Cold Spring Harbor Laboratory)”

This study provided insight into unexpected uses and abuse of oral contraceptive pills by Jordanian males, primarily for bodybuilding, as reported by community pharmacists.

research Normalization of testosterone levels using a low estrogen-containing oral contraceptive in women with polycystic ovary syndrome.

42 citations , July 1982 in “PubMed”

This study found that a low estrogen-containing oral contraceptive normalized hormone levels and improved symptoms in women with polycystic ovary disease, with minimal side effects reported.

research A Review of Gender-Affirming Hormone Therapy for Transgender and Gender Diverse Adults in South Korea

4 citations , January 2022 in “Journal of Menopausal Medicine”

This review discusses gender-affirming hormone therapies in South Korea, detailing the available treatment regimens and associated side effects, but reports no new clinical findings.

research Effect of High Levels of Testosterone on Cardiovascular Risk in Polycystic Ovary Syndrome (PCOS)

July 2020 in “International Journal of Research”

This review examines the development of cardiovascular risk factors related to testosterone levels in PCOS women and reports no new clinical results.

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Community Join

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community Is the combination of spironolactone and estrogen more or less effective than finasteride?

4 upvotes 4 years ago

Spironolactone and estrogen may be more effective for hair regrowth in transgender women than finasteride alone. Estrogen and spironolactone suppress testosterone, potentially reducing DHT more effectively than finasteride.

community High Estrogen and Test on Dut 5x a week

6 upvotes 1 year ago

A user experienced increased pimples and cysts after two years on dutasteride, possibly due to hormonal changes. Suggestions included seeing an endocrinologist, using supplements like boron and DIM, adjusting diet, and reducing body fat to manage side effects.

community Has anyone used topical estrogen or estradiol for hair loss and how effective was it?

in Treatment 1 upvotes 2 years ago

Topical estrogen or estradiol for hair loss is being discussed for its effectiveness compared to finasteride. Users are sharing their experiences and opinions on its potential benefits.

community Just swallowed my first 1mg pill of finasteride! Let the journey begin...

27 upvotes 6 years ago

A user started taking 1mg finasteride for hair loss and plans to follow a thrice-weekly dosing schedule recommended by two doctors. They previously used saw palmetto without issues and are hopeful finasteride won't cause sexual side effects.

community Does having low estrogen make one a better candidate for finasteride?

7 months ago

Low estrogen levels may reduce the risk of side effects from finasteride, such as gynecomastia. Some users plan to start with microneedling and minoxidil before trying finasteride, while others have experienced temporary side effects from topical finasteride but continued use without persistent issues.

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Learn

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learn Ethinylestradiol

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learn Alfatradiol

Alfatradiol: What does a form of estrogen have to do with hair loss in men? Alfatradiol (17α-estradiol) is a prescription topical hormone, licensed for androgenetic alopecia in Germany but not FDA-approved. The controlled trial evidence is in women, where it produced stabilisation rather than regrowth and was outperformed by minoxidil; no comparable placebo-controlled trial in men appears to have been published.

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