July 2024 in “Periodontology 2000” Autologous platelet concentrates show promise in esthetic treatments but need more standardized research.
17 citations
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December 2024 in “Journal of Cosmetic Dermatology” Polynucleotides might work well in esthetic medicine, but more research is needed.
7 citations
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October 2024 in “Cells” PRP therapy shows promise for anti-aging but lacks consistent evidence and standardization.
3 citations
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December 2020 in “Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego” People with androgenetic alopecia often experience high stress, but the stress doesn't affect how the disease progresses or how well different treatments work.
2 citations
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August 2025 in “Pharmaceutics” Polynucleotide (PN) and polydeoxyribonucleotide (PDRN) are DNA-derived biopolymers with distinct roles in dermatology due to differences in polymer length and molecular weight. PN, with longer DNA fragments, is crucial for extracellular matrix remodeling, while PDRN, with shorter sequences, improves skin condition through adenosine receptor activation and supports nucleotide synthesis. This review compares their molecular characteristics and functions, emphasizing their applications in esthetic and regenerative medicine, and highlights recent advances that could inform optimized treatment strategies and evidence-based clinical practice.