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October 2025 in “Current Issues in Molecular Biology” This research found that escin, when applied topically, enhances blood flow in human skin and promotes changes in endothelial cell signaling pathways, suggesting potential benefits for improving cutaneous microcirculation.
January 2026 in “Chonnam Medical Journal” Escin helps keep hair follicles in the growth phase longer.
July 2023 in “Current Issues in Molecular Biology” This study found that escin acts as a natural agonist of the Wnt/β-catenin signaling pathway in cultured human dermal papilla cells by promoting the degradation of GSK-3β, highlighting its potential therapeutic use for conditions like androgenetic alopecia and vitiligo.
August 2025 in “Psychiatry and Clinical Neurosciences Reports” This case report describes a woman who developed trichotillomania during long COVID and saw improvement in symptoms with the SSRI escitalopram.
June 2021 in “Psychiatria Danubina” The antidepressant escitalopram likely caused hair loss in a patient.