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This study found that human hair follicles express erythropoietin and its receptor, suggesting these follicles may use erythropoietin signaling to modulate apoptosis under stress conditions like hypoxia and chemotherapy.

This study found that erythropoietin promotes hair growth by stimulating dermal papilla cells with functional erythropoietin receptors, enhancing hair shaft elongation and anagen phase in cultured human hair follicles and in mice.

In this study, local injection of nanosized recombinant human erythropoietin at the injury site improved skin regeneration and re-epithelialization in a mouse model of deep second-degree burns through coexpression of specific receptors.

Erythropoietin can promote hair growth by increasing IGF-1 in hair cells.

In this study, researchers developed EPO-derived peptides that enhanced hair growth by stimulating dermal papilla cells and increasing IGF-1 expression without triggering systemic erythropoietic effects in tested models, indicating a promising approach for treating hair loss.