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      research Editorial: Crosstalk: skin cells and immune cells in inflammatory skin diseases

      3 citations , August 2024 in “Frontiers in Immunology”
      This source reports that understanding how skin cells and immune cells interact may lead to better treatment options for inflammatory skin diseases like psoriasis and atopic dermatitis, emphasizing the role of epithelial-immune microenvironments in disease pathogenesis.

      research Stem cell dynamics in the hair follicle niche

      135 citations , December 2013 in “Seminars in Cell & Developmental Biology”
      This review examines the literature on the molecular and cellular makeup of the hair follicle niche and how it influences stem cell behavior during hair regeneration, but does not provide new experimental results.

      research Progenitor Cell Dynamics in Androgenetic Alopecia: Insights from Spatially Resolved Transcriptomics

      June 2025 in “International Journal of Molecular Sciences”
      In this study, researchers used spatial transcriptomics to identify increased expression of genes linked to extracellular matrix organization and epithelial–mesenchymal transition in the progenitor cell regions of hair follicles in androgenetic alopecia patients, suggesting a possible role in progenitor cell loss and fibrogenic microenvironment development.

      research Choreographing Immunity in the Skin Epithelial Barrier

      57 citations , March 2019 in “Immunity”
      This review discusses the roles of immune responses and cells in skin health and disease, emphasizing recent insights into their mechanisms and potential therapeutic applications, but presents no new experimental results.

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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 2 years ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss