13 citations
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April 2018 in “Scientific Reports” In this study, genetic variants in the KRT25 and SP6 genes were found to be responsible for curly hair in horses, with the KRT25 variant also causing hypotrichosis due to an epistatic effect.
4 citations
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January 1992 in “American Journal of Ophthalmology”
1 citations
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October 2025 in “Cureus” In this case report, a 30-year-old male with alopecia universalis and autoimmune conditions experienced treatment failure with JAK inhibitors, including ritlecitinib, and developed severe musculoskeletal pain, indicating a potential novel adverse effect that warrants further pharmacovigilance.
1 citations
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March 2025 in “Skin Appendage Disorders” This literature review on JAK inhibitors reports that ocular side effects are rare but could be significant, with an inability to establish a causal link. Clinicians are advised to monitor such adverse events and report them to drug safety agencies.
6 citations
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October 2012 in “BMJ” This case report describes a 37-year-old woman whose recurrent hair shedding was associated with low iron stores and a miscarriage, with improvements seen after increased iron intake.