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Antioxidant Enzyme Expression of mRNA and Protein in the Epididymis of Finasteride-Treated Male Rat Offspring During Postnatal Development

research Antioxidant Enzyme Expression of mRNA and Protein in the Epididymis of Finasteride-Treated Male Rat Offspring During Postnatal Development

2 citations, September 2017 in “Archives of Medical Science”

Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.

research Expression of E-SOD, GPX5 mRNAs and Immunoexpression of Cu/ZnSOD in Epididymal Epithelial Cells of Finasteride-Treated Rats

10 citations, October 2008 in “Andrologia”

Finasteride changes antioxidant enzyme expression, possibly affecting sperm protection in rats.

Histological and Immunohistochemical Examination of the Effect of the Nonsteroidal Antiandrogen Flutamide on Some Organs of the Male Reproductive System in Albino Rats

research Histological and Immunohistochemical Examination of the Effect of the Nonsteroidal Antiandrogen Flutamide on Some Organs of the Male Reproductive System in Albino Rats

September 2012 in “The Egyptian Journal of Histology”

Flutamide caused damage to male rat reproductive organs and may affect fertility.

research Testosterone Up-Regulates Vacuolar ATPase Expression and Functional Activities in Vas Deferens of Orchidectomized Rats

2 citations, December 2017 in “Theriogenology”

Testosterone increases acidification in the vas deferens by up-regulating V-ATPase.

research HaCaT Cell Proliferation Influenced by Melatonin

28 citations, January 2003 in “Skin pharmacology and physiology”

Melatonin affects skin cell growth differently based on how much and how long it's used.

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Community Join

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community DHT Isn't (Directly) Important

in Research/Science 95 upvotes 2 weeks ago

Finasteride's potential side effects, especially sexual dysfunction, are discussed, with emphasis on hormonal balance between testosterone and estradiol. Users share experiences with finasteride, minoxidil, and dutasteride, highlighting the variability in side effects and the influence of mindset and lifestyle.

community Ejaculation & balding: NoFap has helped me stop my hair loss [case study]

37 upvotes 8 years ago

The user claims NoFap (abstaining from pornography, masturbation, and orgasm) helped stop their hair loss. Others argue that hair loss is primarily due to genetics and DHT, which can be managed with finasteride.

community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 11 months ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 1 year ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.