100 citations
,
August 2008 in “American Journal Of Pathology” This study found that epidermal VEGF is crucial for maintaining skin barrier function in mice and may help explain psoriasis development following skin trauma due to its effects on angiogenesis and hyperplasia.
41 citations
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January 2015 in “Development” This study found that inducing Atoh1 expression in transgenic mice is sufficient to generate new Merkel cells in the epidermis, with variations by skin location, developmental age, and hair cycle stage.
33 citations
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January 2000 in “Acta Oto-Laryngologica” In this study, epidermal growth factor (EGF) was shown to increase the length of rat organ of Corti segments containing supernumerary hair cells, with the effect peaking at birth and independent of cell division.
10 citations
,
November 2015 in “Experimental Dermatology” The study observed that mRAGE expression is prevalent in keratinocytes of the healthy human epidermis and may regulate inflammation and apoptosis to maintain skin homeostasis rather than responding to aging processes.
8 citations
,
February 2020 in “Journal of Drug Delivery Science and Technology” This study demonstrated that using PLGA nanoparticles to deliver chlorogenic acid significantly increased type 17 collagen production in human epidermal cells, indicating potential for improved skincare formulations.