44 citations
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July 2016 in “Stem Cells Translational Medicine” This study demonstrated that cultured epidermal stem cells and skin-derived precursors can regenerate functional hair follicles and sebaceous glands in both mice and adult humans, suggesting potential for bioengineered skin substitutes.
5 citations
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April 2021 in “Biomedicines” This study found that engineered skin substitutes made with skin-derived precursors and epidermal stem cells can regenerate hair follicles after grafting into nude mice.
1 citations
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September 2022 in “Biomaterials advances” This study used 3D bioprinting to implant epidermal stem cells, skin-derived precursors, and Matrigel into mouse wounds, successfully regenerating hair follicles and skin components within four weeks, with minimal impact on stem cell viability and stemness.
February 2025 in “Theranostics” In this study, researchers used 3D bioprinting with skin stem cells and specific hydrogels to create artificial skin that successfully promoted complete wound healing and the regeneration of skin structures, including hair follicles and blood vessels, in mice.
This study reviewed various methods and techniques aimed at overcoming limitations in culturing human hair follicles, specifically focusing on restoring the inductivity of hair follicle cells for successful hair regeneration.
