January 2022 in “Archiv für Tierzucht” This study found that EPHA4 and Ephrin A3 genes are differentially expressed during hair follicle development in fine-wool sheep, suggesting roles in follicle regeneration and density.
August 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that KrasG12D mutant cells are typically cleared from adult pancreas tissues through mechanisms involving the EphA2 receptor, suggesting its role as a tumor suppressor in pancreatic cancer.
42 citations
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October 2011 in “Seminars in Cell & Developmental Biology” This review explores the role of Eph receptors and ephrins in skin cell processes, discussing their potential for therapeutic targeting in dermatological disorders, but it presents no new research findings.
September 2025 in “Blood Advances” This study found that targeting androgen receptors with prostate cancer drugs ARN509 and finasteride induced remission and increased survival in a leukemia mouse model, suggesting a potential new treatment approach for acute myeloid leukemia.
15 citations
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July 2008 in “Journal of Dermatological Science” This study found that ephrin-A3 accelerates hair follicle development and increases hair follicle density in neonatal mice, suggesting its involvement in hair growth regulation.