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5 / 12 resultslearn Finasteride
Frontline, gold standard treatment for combatting androgenic alopecia
learn Saw Palmetto
a natural and far less effective alternative to Finasteride
learn Melatonin
hormone commonly taken for sleep aid has some topical benefits for hair
learn Valproic acid
an anticonvulsant repurposed for hair loss via histone inhibition
Research
5 / 1000+ results![Inhibition of Human Steroid 5β-Reductase (AKR1D1) by Finasteride and Structure of the Enzyme-Inhibitor Complex](/images/research/ac427dd8-e232-4361-bb09-b6fc8079c74a/small/2888.jpg)
research Inhibition of Human Steroid 5β-Reductase (AKR1D1) by Finasteride and Structure of the Enzyme-Inhibitor Complex
Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.
![Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition](/images/research/f55f411a-9859-45d1-ba63-d926be8584df/small/15260.jpg)
research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
![Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases](/images/research/d8ce08f7-330c-47b2-83cc-7f1f5be83619/small/14505.jpg)
research Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases
Certain drugs that block specific enzymes can help treat prostate diseases.
![Does Inhibition of Aldose Reductase Contribute to the Anti-Inflammatory Action of Setipiprant?](/images/research/bb6da569-2e33-4e67-b2e2-d61d06cfae6b/small/18173.jpg)
research Does Inhibition of Aldose Reductase Contribute to the Anti-Inflammatory Action of Setipiprant?
Setipiprant may reduce inflammation by blocking an enzyme called aldose reductase.
![Structural & functional studies of L-PGDS and SMPDL3A enzymes in lipid signaling family](/images/research/23c8c71d-c7b6-4a57-93f8-5d373e42fce8/small/37007.jpg)
research Structural & functional studies of L-PGDS and SMPDL3A enzymes in lipid signaling family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
Community Join
5 / 486 resultscommunity Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?
The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.
community The theory that explains everything. Please help me make this big!
The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.
community u/joaopassos4444 has zero education in endocrinology, human biology or science, it’s incredibly unlikely he good Will Hunting-ed a medical issue that stumped researchers for thousands of years, please stop buying random supplements based on layman speculation and temper your expectations
User questions credibility of a hair loss "cure" found by a non-expert and warns against wasting money on unproven supplements. Others discuss trying natural extracts and the importance of researching the enzyme 3ADH for potential hair growth benefits.
community Saying creatine causes loss on fin/dut makes no sense and this is why
The conversation discusses whether creatine causes hair loss for those using finasteride or dutasteride, with some suggesting creatine might increase DHT or upregulate androgen receptors, potentially leading to hair loss. Others argue the evidence is not conclusive, citing limited studies and personal anecdotes, with some avoiding creatine as a precaution.
community Buzzed my hair today. Raised my confidence a lot.
A user who buzzed their hair, raising their confidence. Other users suggested trying finasteride to thicken the existing hair or using hair systems as an alternative. Additionally, toppik was suggested as a way to fill in thinning areas.