May 2026 in “Bioactive Materials” This study reported that in degenerative alopecia, Zn²⁺/Cu²⁺-dependent proteases are downregulated and destabilized, and a specially developed microneedle patch reactivated these enzymes, reduced senescence, and enhanced hair regeneration in an animal model.
This study found that selective deletion of PIKFyve kinase using a PF4 promoter in mice led to defective platelet lysosome biogenesis and a prothrombotic effect, with unexpected macrophage infiltration in multiple organs.
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August 1981 in “American Journal of Veterinary Research” This study demonstrates that glucocorticoid hepatopathy in Beagle dogs led to rapid and lasting clinical, morphologic, and biochemical changes, which may aid in the future diagnosis and prognosis of similar conditions.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Blocking IL-1 could help treat some hair loss conditions; alopecia affects liver detox systems; spironolactone is better than finasteride for female hair growth; focusing on the catagen hair phase could lead to new alopecia treatments.
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April 2015 in “The FASEB journal” In this study using SKH-1 mice, researchers observed that acute UVB exposure increased expression of retinoid metabolism proteins and decreased retinol storage enzyme levels, suggesting enhanced retinoic acid synthesis in the epidermis.