3 citations
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June 2018 in “Bioorganic & medicinal chemistry” This study identified that derivatives 4, 4b, and 4c strongly inhibited the enzyme type 1 5α-reductase and decreased reproductive organ weights in hamsters, suggesting potential as prodrugs for prostate tumor growth inhibition.
11 citations
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April 2012 in “Journal of Investigative Dermatology” A specific mutation in PA-PLA1α causes abnormal hair growth.
March 2024 in “Molecules/Molecules online/Molecules annual” This study optimized the extraction process of bear grease through enzymatic hydrolysis and found that it was rich in unsaturated fatty acids, enhancing its hair growth-promoting properties in mice compared to traditional methods.
5 citations
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March 2019 in “Journal of lipid research” This study reports new fluorogenic ceramidase substrates and highlights RBM14C24:1 as an efficient substrate for neutral ceramidase, while RBM15C18:1 is the best probe for measuring ACER1 and ACER2 activities, potentially aiding high-throughput screening for ceramidase inhibitors.
This study identified pectin in early immature durian fruits and found that pectin-oligosaccharides derived from them show stronger antioxidant and antiglycation activities, with potential applications in cosmetic products.