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GlossaryEndothelial Nitric Oxide Synthase (eNOS)

enzyme producing nitric oxide to relax blood vessels

Endothelial Nitric Oxide Synthase (eNOS) is an enzyme found in the cells lining blood vessels. It produces nitric oxide, a molecule that helps relax and widen blood vessels, improving blood flow and reducing blood pressure. This enzyme plays a crucial role in cardiovascular health and is also involved in processes like wound healing and hair growth.

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research Anti-SARS-CoV-2 Action of 5α-Reductase Inhibitors May Be Mediated by Dehydroepiandrosterone

1 citations, February 2022 in “The Journal of Urology”

Certain drugs like Dutasteride and Finasteride might help fight SARS-CoV-2 by increasing levels of a steroid called DHEA, which can protect the heart and increase nitric oxide to counteract the virus.

research Nothopanax Scutellarium: Natural Hair Growth Plant

June 2025 in “Pharmacon Jurnal Farmasi Indonesia”

Mangkokan leaves may help hair growth and health.

research Topically Applied N,N-Dimethylglycine Sodium Salt Enhances Human Skin Blood Flow by Inducing Endothelial Nitric Oxide Release

May 2024 in “The journal of investigative dermatology/Journal of investigative dermatology”

Applying DMG-Na to the skin increases blood flow and may help with skin conditions.

research Effect of Minoxidil on Trabecular Outflow via the Paracellular Pathway

January 2020 in “Korean journal of ophthalmology/Korean Journal of Ophthalmology”

Minoxidil increases cell layer permeability by reducing tight junction proteins and raising ROS levels.

research Efficacy of Platelet-Rich Plasma and Concentrated Growth Factor in Treating Androgenetic Alopecia: A Retrospective Study

5 citations, January 2020 in “Annals of maxillofacial surgery”

PRP and CGF treatments help with hair growth and density in androgenetic alopecia.

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community Long term finasteride users; Did you notice any improvement after 2 years?

in Finasteride/Dutasteride 14 upvotes 2 years ago

Long term Finasteride users and whether or not they have noticed improvements after two years of use, with other treatments such as Minoxidil and dermarolling also discussed. Some replies suggest that improvement is possible even beyond the two year mark while others caution against believing studies backed by the Post-Finasteride Foundation.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

in Finasteride/Dutasteride 191 upvotes 3 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

community Is someone like Elon Musk still on fin and min after hair transplant?

in Transplants 2 years ago

Hair loss treatments, specifically finasteride and minoxidil, being used by wealthy individuals to combat their genetic predisposition to baldness. It also discussed other potential treatments such as RU58841 and dutasteride.