This study found that a mesenchymal stromal cell-derived regenerative extracellular matrix (rECM) significantly accelerated wound closure and improved healing in diabetic mice, also enhancing nerve and blood vessel formation compared to controls.
162 citations
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July 2011 in “Biomacromolecules” This study found that chitosan nanofibrillar scaffolds accelerated skin wound healing in mice by enhancing cell adhesion, proliferation, and regeneration of epidermis and dermis compared to other forms.
This study found that conditioned medium from human placental cells or tissue promoted angiogenesis in HUVECs in vitro, with early-pregnancy placental cells and whole placental tissue showing more significant effects.
14 citations
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April 2017 in “Scientific Reports” This study demonstrated that using a perfusion culture bioreactor and 3D spheroid culture can enhance corneal endothelial cell expansion and support the construction of tissue-engineered corneal endothelial layers in vitro.
December 2009 in “Saengmyeong gwahag hoeji/Saengmyeong gwahak hoeji” This study observed that thymosin beta 4 and VEGF have similar expression patterns in various human tissues, suggesting a role in angiogenesis and organ function.