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Attenuation of 5α-Reductase-Mediated Progesterone Metabolism Promotes Differentiation of Human Endometrial Stromal Cells for the Establishment of Pregnancy

research Attenuation of 5α-Reductase-Mediated Progesterone Metabolism Promotes Differentiation of Human Endometrial Stromal Cells for the Establishment of Pregnancy

January 2020 in “Nihon Yakuri Gakkai nenkai yoshishu”

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

Overactivated Sonic Hedgehog Signaling Aggravates Intrauterine Adhesion by Inhibiting Autophagy in Endometrial Stromal Cells

research Overactivated Sonic Hedgehog Signaling Aggravates Intrauterine Adhesion by Inhibiting Autophagy in Endometrial Stromal Cells

52 citations , September 2020 in “Cell Death and Disease”

Overactive sonic hedgehog signaling worsens uterine scarring by reducing cell recycling.

research Effects of Platelet-Rich Fibrin on Human Endometrial Stromal Cells Behavior in Comparison to Platelet-Rich Plasma

1 citations , September 2024 in “Frontiers in Cell and Developmental Biology”

PRF is better than PRP for endometrial repair.

research Alleviation of Severe Skin Insults Following High-Dose Irradiation with Isolated Human Fetal Placental Stromal Cells

1 citations , November 2022 in “International journal of molecular sciences”

Human fetal placental stromal cell injections speed up healing and improve skin and hair recovery after radiation damage.

A Role for Steroid 5 Alpha-Reductase 1 in Vascular Remodeling During Endometrial Decidualization

research A Role for Steroid 5 Alpha-Reductase 1 in Vascular Remodeling During Endometrial Decidualization

May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

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Community Join

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community Taking Charge of Your Hair: The "Big 3 Stack" Explained for 2023

in Research/Science 129 upvotes 2 years ago

The "Big 3 Stack" for hair loss treatment, which includes Minoxidil for hair density improvement, Ketoconazole shampoo for enhancing hair volume and thickness, and Finasteride for blocking hair loss causing hormones. Microneedling can boost Minoxidil's effects.

The story of RU58841/ PSK3841

community The story of RU58841/ PSK3841

by

Typical-Promise-3001 in Research 622 upvotes 1 year ago

RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

community Results are in for my experiment with Creatine/Fin

in Finasteride 130 upvotes 6 years ago

Creatine use with finasteride increased DHT levels, possibly affecting hair loss. The user plans to reduce creatine to stabilize DHT and hair shedding.