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research Stromal Cells of the Human Postmenopausal Ovary Display a Distinctive Biochemical and Molecular Phenotype

June 2003 in “Obstetrical & Gynecological Survey”

Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.

Supraphysiological Dose of Testosterone Impairs the Expression and Distribution of Sex Steroid Receptors During Endometrial Receptivity Development in Female Sprague-Dawley Rats

research Supraphysiological Dose of Testosterone Impairs the Expression and Distribution of Sex Steroid Receptors During Endometrial Receptivity Development in Female Sprague-Dawley Rats

September 2024 in “International Journal of Molecular Sciences”

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

research The Emerging Roles of N6-Methyladenosine (m6A) Deregulation in Polycystic Ovary Syndrome

3 citations , May 2025 in “Journal of Ovarian Research”

m6A deregulation plays a key role in PCOS and could lead to new treatments.

Dysregulation of Leukemia Inhibitory Factor (LIF) Signaling Pathway by Supraphysiological Dose of Testosterone in Female Sprague Dawley Rats During Development of Endometrial Receptivity

research Dysregulation of Leukemia Inhibitory Factor (LIF) Signaling Pathway by Supraphysiological Dose of Testosterone in Female Sprague Dawley Rats During Development of Endometrial Receptivity

January 2025 in “Biomedicines”

High testosterone levels can harm fertility by disrupting the LIF signaling pathway in the uterus.

Intrauterine Botulinum Toxin A Administration Promotes Endometrial Regeneration Mediated by IGFBP3-Dependent OPN Proteolytic Cleavage in Thin Endometrium

research Intrauterine Botulinum Toxin A Administration Promotes Endometrial Regeneration Mediated by IGFBP3-Dependent OPN Proteolytic Cleavage in Thin Endometrium

9 citations , January 2023 in “Cellular and Molecular Life Sciences”

Botulinum toxin A can help improve thin endometrium and embryo implantation.

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community Taking Charge of Your Hair: The "Big 3 Stack" Explained for 2023

in Research/Science 129 upvotes 2 years ago

The "Big 3 Stack" for hair loss treatment, which includes Minoxidil for hair density improvement, Ketoconazole shampoo for enhancing hair volume and thickness, and Finasteride for blocking hair loss causing hormones. Microneedling can boost Minoxidil's effects.

community The story of RU58841/ PSK3841

Typical-Promise-3001 in Research 622 upvotes 1 year ago

RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

community Results are in for my experiment with Creatine/Fin

in Finasteride 130 upvotes 6 years ago

Creatine use with finasteride increased DHT levels, possibly affecting hair loss. The user plans to reduce creatine to stabilize DHT and hair shedding.