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research Research Snippets: Dermatological Genetics and Conditions

July 2005 in “British Journal of Dermatology”

New gene mutations linked to skin conditions were found, bacteria and chemicals may worsen acne, a dog mutation could exist in humans, virus-like elements might be involved in psoriasis, and a vitamin D3 treatment doesn't prevent chemotherapy-related hair loss.

H3K9me3 Methyltransferase SETDB1 Controls Retrotransposon Silencing, DNA Methylation, Constitutive Heterochromatin Maintenance and 3D-Chromatin Structure in Epidermal Keratinocytes

research H3K9me3 Methyltransferase SETDB1 Controls Retrotransposon Silencing, DNA Methylation, Constitutive Heterochromatin Maintenance and 3D-Chromatin Structure in Epidermal Keratinocytes

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.

research Alopecia in Harlequin Mutant Mice Is Associated with Reduced AIF Protein Levels and Expression of Retroviral Elements

4 citations, December 2020 in “Mammalian genome”

Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.

research The Hair Follicle as a Dynamic Mini-Organ

759 citations, February 2009 in “Current Biology”

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

research Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: Annotated Tables

86 citations, December 2001 in “Experimental dermatology”

Mutant mice help researchers understand hair growth and related genetic factors.

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Community Join

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community Using Fin and Alfatradiol in conjunction?

in Finasteride/Dutasteride 5 upvotes 2 years ago

User considers adding Alfatradiol to their topical finasteride treatment for hair loss. Others discuss Alfatradiol as a weak estrogen and 5α-reductase inhibitor used for pattern hair loss in men and women.

community Pre Fin Bloodwork To Check Other Potential Issues

in Chat 21 upvotes 3 years ago

A user preparing to start finasteride for hair loss wanted to check for any abnormal bloodwork related to hair loss. They shared their blood test results and learned from another user that their doctor prescribed finasteride without any preliminary tests.

community Having androgen receptor density and sensitivity at wrong f*ing place

in Satire 7 upvotes 1 month ago

The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

community My hair after 3 steroid cycles

in Progress Pictures 25 upvotes 4 months ago

A user shared their hair progress after three steroid cycles, using 5% minoxidil and 100mg RU58841 daily. They are considering a hair transplant due to paranoia about shedding.

community I am horny as hell due to fin.

in Finasteride/Dutasteride 225 upvotes 10 months ago

Some individuals taking finasteride for hair loss report increased libido and frequent masturbation, with no immediate hair regrowth but darker hair appearance. A dermatologist explains that finasteride may raise testosterone levels temporarily, which could lead to increased sex drive in some people.

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