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research Expression of Foxi3 is regulated by ectodysplasin in skin appendage placodes

43 citations , February 2013 in “Developmental dynamics”

This study found that Eda and activin A regulate Foxi3 expression, which may contribute to the development of hypohidrotic ectodermal dysplasia by affecting Foxi3 activity in ectodermal appendages like hair and teeth.

research Hair growth control by follistatin

January 2004 in “Enshou saisei”

This study observed that follistatin and activin interactions significantly influence hair follicle development in mice, suggesting potential regenerative treatments for alopecia.

research 1338 Dermal Wnt/β-catenin activation tunably controls hair follicle initiation

May 2018 in “Journal of Investigative Dermatology”

Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.

research Retinoic Acid and Mouse Skin Morphogenesis. II. Role of Epidermal Competence in Hair Glandular Metaplasia

16 citations , November 1994 in “Developmental Biology”

Retinoic acid causes gland formation instead of hair in mouse skin by altering epidermal and dermal interactions.

research Identification of Ectodysplasin Target Genes Reveals the Involvement of Chemokines in Hair Development

48 citations , January 2012 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study identified chemokine receptor ligands cxcl10 and cxcl11 as new hair-specific transcriptional targets of the Eda pathway, suggesting chemokine signaling plays a role in primary hair follicle patterning.

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community Hair and normal skin created from human pluripotent stem cells for the first time

86 upvotes 6 years ago

Human pluripotent stem cells have been used to create hair and skin, potentially offering a new solution for baldness. A user also mentioned starting finasteride but experiencing unexpected hair thinning.

community I Guess balding is cured so should we close subreddit and move to hairstyling photos 😁 Botox-like nerve blocking reveals potential way to fully regenerate skin without scarring

5 months ago

Baldness is difficult to cure because current treatments like finasteride, dutasteride, and minoxidil only prevent hair shedding, and new developments are mostly ineffective. Botox shows potential in aiding skin regeneration and hair growth, but maintenance therapy with treatments like dutasteride and minoxidil may still be necessary.

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