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research An unusual presentation of vitamin D dependent rickets type 2 with low 25 (OH) D3 levels and alopecia: a case report of two siblings

July 2022 in “International Journal of Contemporary Pediatrics”

This report describes siblings with vitamin D-dependent rickets type 2, characterized by growth retardation, alopecia totalis, and low 25(OH)D3 levels, highlighting its autosomal recessive pattern and distinction from other rickets types.

A Rare Case of Hereditary 1,25-Dihydroxyvitamin D Resistant Rickets

research 6874 A Rare Case Of Hereditary 1,25 (OH)2D Resistant Rickets

October 2024 in “Journal of the Endocrine Society”

This case study reports on a rare form of vitamin D resistant rickets in a 37-year-old male, highlighting the condition's clinical features and the necessity for a thorough understanding of calcium and vitamin D metabolism in the diagnosis and management of metabolic bone diseases.

research SUN-332 A Rare Case Of Hereditary 1,25 (OH)2D Resistant Rickets

October 2024 in “Journal of the Endocrine Society”

This study highlights a rare case of vitamin D-dependent rickets type 2A caused by a heterozygous mutation in the vitamin D receptor gene, emphasizing the complexity of managing this condition with high-dose calcium and vitamin D therapy.

research Hereditary vitamin D-resistant rickets (HVDRR) owing to a heterozygous mutation in the vitamin D receptor

37 citations , August 2011 in “Journal of Bone and Mineral Research”

This study reported a case of hereditary vitamin D–resistant rickets caused by a single heterozygous missense mutation in the VDR gene, showing dominant-negative effects and reduced response to 1,25-dihydroxyvitamin D3.

research Rickets with alopecia: An inborn error of vitaminD metabolism

170 citations , May 1979 in “The journal of pediatrics/The Journal of pediatrics”

This report describes two sisters with rickets and alopecia unresponsive to high doses of vitamin D2, where oral phosphorus supplements led to significant clinical improvement.

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community When you use 1 mg fin vs you use 2.5 mg dut

2446 upvotes 4 months ago

Switching from finasteride to dutasteride can lead to varied results, with some experiencing better hair regrowth and fewer side effects, while others continue to lose hair. Dutasteride is generally seen as more effective but has a longer half-life, potentially extending side effects.

community 1 Year Finasteride + 2.5 Oral Minoxidil

in Progress Pictures 606 upvotes 1 year ago

Significant hair regrowth was achieved using finasteride and 2.5mg oral minoxidil over a year, despite initial shedding. The treatment is recommended, though it may cause increased heart rate and body hair growth.

community 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?

27 upvotes 1 year ago

Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.

community Next month marks 2 years on Dutasteride. When does it start working?

in Finasteride/Dutasteride 36 upvotes 2 years ago

A user has been on dutasteride for nearly 2 years with no improvement in hair loss, expressing frustration. Other users suggest checking for other health conditions, getting bloodwork, and considering stopping TRT or trying finasteride.

community Dutasteride Vs. Testosterone, who wins?

in Finasteride/Dutasteride 58 upvotes 2 years ago

The conversation discusses whether 2.5mg of dutasteride or 200mg of testosterone weekly is more influential in preventing hair loss, with various personal experiences indicating that the effectiveness is dependent on the individual's genetic profile. Some users report that dutasteride is likely to be more effective at the given doses.

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