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GlossaryElectrospray Ionization Mass Spectrometry

analyzes molecules by converting them into charged particles

Electrospray Ionization Mass Spectrometry (ESI-MS) is a technique used to analyze the mass and structure of molecules by converting them into charged particles (ions) using an electric field. This method is particularly useful for studying large biomolecules like proteins and peptides, as it allows for the gentle ionization of these complex structures without breaking them apart.

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Finasteride Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Ionization Tandem Mass Spectrometry: Application to a Comparative Pharmacokinetics Study

research Finasteride Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Ionization Tandem Mass Spectrometry: Application to a Comparative Pharmacokinetics Study

1 citations , April 2015 in “Drug research”

New method measures finasteride in plasma, finds two formulations bioequivalent.

Ultra-Performance Liquid Chromatography with Electrospray Ionization Tandem Mass Spectrometry for the Determination of Ketoconazole in Anti-Dandruff Shampoo

research Ultra-Performance Liquid Chromatography with Electrospray Ionization Tandem Mass Spectrometry for the Determination of Ketoconazole in Anti-Dandruff Shampoo

1 citations , February 2014 in “Analytical Letters”

The method accurately measures the amount of ketoconazole in anti-dandruff shampoo and cream, and can also be used to monitor the drug in human plasma.

Determination of Finasteride in Human Plasma by Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry with Flow Rate Gradient

research Determination of Finasteride in Human Plasma by Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry with Flow Rate Gradient

2 citations , October 2010 in “European Journal of Drug Metabolism and Pharmacokinetics”

Researchers developed a quick and sensitive way to measure finasteride in blood using a small sample size.

research Highly Sensitive Simultaneous Measurement of Steroid Hormone in Human Serum by Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry

March 2022 in “VNU Journal of Science Medical and Pharmaceutical Sciences”

A new method accurately measures nine steroid hormones in human serum with high sensitivity.

research Simultaneous Quantitation of Nine Hydroxy-Androgens and Their Conjugates in Human Serum by Stable Isotope Dilution Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry

22 citations , January 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

A new method accurately measures nine specific hormones in human blood.

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community Finasteride does deplete important nuero-active steroids

in Research/Science 9 upvotes 2 years ago

Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.