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GlossaryArachidonic Acid (5,8,11,14-Eicosatetraenoic Acid)

polyunsaturated omega-6 fatty acid involved in inflammation and signaling

Arachidonic Acid (AA) is a polyunsaturated omega-6 fatty acid that is a key component of cell membranes. It plays a crucial role in the body's inflammatory response and is a precursor to various signaling molecules called eicosanoids, which include prostaglandins, thromboxanes, and leukotrienes. These molecules are involved in processes such as inflammation, immunity, and the regulation of blood pressure.

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research Human Essential Fatty Acid Deficiency: Treatment by Topical Application of Linoleic Acid

14 citations, July 1977 in “PubMed”

Applying linoleic acid to the skin fixed essential fatty acid deficiency symptoms.

research Fatty Acids and Related Lipid Mediators in the Regulation of Cutaneous Inflammation

28 citations, January 2018 in “Biochemical Society Transactions”

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

research Docosahexaenoic Acid Slows Inflammation Resolution and Impairs the Quality of Healed Skin Tissue

8 citations, November 2019 in “Clinical Science”

High DHA levels delay wound healing and worsen skin repair quality.

research Cytochrome P450: A Target for Drug Development for Skin Diseases

115 citations, August 2004 in “The journal of investigative dermatology/Journal of investigative dermatology”

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

research Tumor Promotion in Skin: Are Active Oxygen Species Involved?

10 citations, January 1985 in “Elsevier eBooks”

Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.

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